RARE
Neutral signalScored 2026-10-25 Drivers: Congress, trend, fundamentals. Moteurs : Congrès, tendance, fondamentaux.
Research, not advice.
À propos
Ultragenyx Pharmaceutical Inc.
- Nom
- Ultragenyx Pharmaceutical Inc.
- Secteur
- Healthcare
- Industrie
- Biotechnology
- Bourse
- NASDAQ
- Capitalisation
- $1.5B
- Employés
- 1,371
- PDG
- Emil D. Kakkis
- Site web
- https://www.ultragenyx.com
- Marché
- ABEOBBIOBMRNFDMTMGTXMREO
Ultragenyx Pharmaceutical Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing innovative treatments for rare and ultra-rare genetic conditions. Its operations span North America, Europe, and other international markets. The company's portfolio of marketed biologic products addresses several serious diseases. This includes Crysvita (burosumab), an antibody that targets fibroblast growth factor 23, used to treat X-linked hypophosphatemia and tumor-induced osteomalacia. Mepsevii offers enzyme replacement therapy for both pediatric and adult patients suffering from Mucopolysaccharidosis VII. Dojolvi is available for individuals with long-chain fatty acid oxidation disorders, while Evkeeza (evinacumab) provides a treatment option for homozygous familial hypercholesterolemia. Ultragenyx also boasts a robust pipeline of investigational therapies. Notable candidates include DTX401, an adeno-associated virus 8 (AAV8) gene therapy for glycogen storage disease type Ia, and DTX301, another AAV8 gene therapy aimed at ornithine transcarbamylase deficiency. Other promising developments feature UX143, a human monoclonal antibody for osteogenesis imperfecta; GTX-102, an antisense oligonucleotide designed for Angelman syndrome; UX701, targeting Wilson disease; and UX053, in development for glycogen storage disease type III. To advance its research and development efforts, Ultragenyx Pharmaceutical Inc. maintains strategic collaboration and licensing agreements with numerous partners, such as Kyowa Kirin Co., Ltd., Saint Louis University, REGENXBIO Inc., Bayer Healthcare LLC, GeneTx, Mereo, University of Pennsylvania, Arcturus Therapeutics Holdings Inc., Solid Biosciences Inc., and Daiichi Sankyo Co., Ltd. The company was founded in 2010 and operates from its headquarters in Novato, California.
Price (1 year)
Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.
Decouvert par les declarations du Congres
- Insiders
- —
- Total bought
-
—
Avg buy (VWAP, 90d window) —
- Total sold
-
$291,933
Avg sell (VWAP, 90d window) $19.33 vs last close $16.08 (-16.8%)
Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.
$181,783 of that total is under a Rule 10b5-1 plan. It is shown here and left out of the score.
- Last activity
- —
- Liquidity
- Liquid $58,939,599/day · 20d vol
- Last synced
-
2026-10-26 21:10:54
Sign in to request a sync of this company's price history and timing levels.
Insider holdings as a share of total assets aren't available for this company.
Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.
Recent Form 4
Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.
| Date | Person | Side | Shares | Price | Value | Form 4 |
|---|---|---|---|---|---|---|
| 2026-10-15 | Horn Howard | Sell · S | 7,066 | $15.27 | $107,898 | Form 4 |
| 2026-09-15 | Huizenga Theodore Alan | Sell · S · 10b5-1 | 1,283 | $13.57 | $17,410 | Form 4 |
| 2026-09-03 | Huizenga Theodore Alan | Sell · S | 161 | $13.99 | $2,252 | Form 4 |
| 2026-08-03 | Horn Howard | Sell · S · 10b5-1 | 4,696 | $24.92 | $117,024 | Form 4 |
| 2026-08-03 | Parschauer Karah Herdman | Sell · S · 10b5-1 | 1,900 | $24.92 | $47,348 | Form 4 |
Sales marked 10b5-1 are scheduled in advance and don't count toward the Quorum score. Les ventes marquées 10b5-1 sont planifiées à l'avance et ne pèsent pas dans le score Quorum.
Congressional trades
STOCK Act disclosures (90-day window)
Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.
| Date | Member | Side | Amount range | Filing |
|---|---|---|---|---|
| 2026-09-29 | Gilbert Cisneros | Buy | $1,001 - $15,000 | Filing |
Recent trades
| Date | Representative | Type | Amount |
|---|---|---|---|
| 2026-09-29 | Gilbert Cisneros | Purchase | $1,001 - $15,000 |
| 2026-03-03 | Gilbert Cisneros | Purchase | $1,001 - $15,000 |
| 2026-02-18 | Gilbert Cisneros | Purchase | $1,001 - $15,000 |
| 2025-08-08 | Gilbert Cisneros | Purchase | $1,001 - $15,000 |
| 2025-07-15 | Gilbert Cisneros | Purchase | $1,001 - $15,000 |
| 2022-01-21 | Ro Khanna | Sale | $1,001 - $15,000 |
| 2022-01-11 | Ro Khanna | Sale | $1,001 - $15,000 |
| 2021-08-30 | Kurt Schrader | Purchase | $1,001 - $15,000 |
Signal
Neutral signalScored 2026-10-25 Drivers: Congress, trend, fundamentals. Moteurs : Congrès, tendance, fondamentaux.
RARE presents a moderate event-driven signal anchored by congressional purchases and two significant PRV sales ($203M and $210M) providing non-dilutive cash injections, partially offsetting deeply stressed fundamentals.
The first sentence of the analysis written for RARE on 2026-10-25 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.
Factor checklist — research, not advice
A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.
- Insider Pulls against a bullish reading. Selling cluster — sale value, no purchase value
- Narrative Unavailable or mixed. Stored narrative reading is in the neutral band
- Congress Supports a bullish reading. 3 purchase disclosures year to date
- Timing Pulls against a bullish reading. Close is more than 0.5 ATR under stored support
- Financial indicators Unavailable or mixed. Current ratio 2.48 · operating margin -79% — readings disagree
Suggested stop 14.50, nearest stored support minus 0.5 ATR(9.8% under the last close). Reward/risk to the next stored resistance is 4.14. Research, not advice. Not an order.
Recent news
- 2026-10-20 Ultragenyx Pharmaceutical (NASDAQ:RARE) CFO Howard Horn Sells 7,066 Shares of Company Stock Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE - Get Free Report) CFO Howard Horn sold 7,066 shares of the company''s stock in a transaction dated Thursday, October 15th. The stock was sold at an average price of $15.27, for a total value of $107,897.82. Following the completion of the transaction, the chief financial officer owned 89,229 shares of
- 2026-10-15 RARE''s Fayuvi Approval Spurs Second PRV Sale Worth $203M in a Week Ultragenyx agrees to sell its Fayuvi-linked PRV for $203 million, marking its second voucher sale in one week and adding non-dilutive funding for rare-disease programs.
- 2026-10-14 Can RARE''s Approved Product Portfolio Drive Its Next Growth Phase? Ultragenyx''s established rare-disease treatments continue to support revenue growth, while two newly approved gene therapies offer additional commercial opportunities.
- 2026-10-14 Ultragenyx Enters into Agreement to Sell Rare Pediatric Disease Priority Review Voucher for $203 Million Agreement marks the Company''s second PRV sale within one week, following the previously announced GENGLYCOS™ PRV transaction Agreement marks the Company''s second PRV sale within one week, following the previously announced GENGLYCOS™ PRV transaction
- 2026-10-14 Rep. Gilbert Ray Cisneros, Jr. Acquires Shares of Taiwan Semiconductor Manufacturing Company Ltd. (NYSE:TSM) Representative Gilbert Ray Cisneros, Jr. (Democratic-California) recently bought shares of Taiwan Semiconductor Manufacturing Company Ltd. (NYSE: TSM). In a filing disclosed on October 12th, the Representative disclosed that they had bought between $1,001 and $15,000 in Taiwan Semiconductor Manufacturing stock on September 22nd. The trade occurred in the Representative''s "150 MAIN STREET TRUST > BANK OF
- 2026-10-12 Analyzing Atara Biotherapeutics (NASDAQ:ATRA) & Ultragenyx Pharmaceutical (NASDAQ:RARE) Atara Biotherapeutics (NASDAQ: ATRA - Get Free Report) and Ultragenyx Pharmaceutical (NASDAQ: RARE - Get Free Report) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, valuation, analyst recommendations, risk, institutional ownership, earnings and profitability. Profitability This table compares Atara Biotherapeutics and
- 2026-10-08 Ultragenyx to Sell Rare Pediatric Disease PRV for $210M to Boost Cash RARE enters into an agreement to sell a Rare Pediatric Disease PRV for $210M, adding non-dilutive cash as it advances rare-disease therapies.
- 2026-10-07 Ultragenyx shares rise after agreeing to sell FDA priority review voucher for $210 million Ultragenyx Pharmaceutical (NASDAQ:RARE) shares rose over 3.2% on Wednesday morning after the biopharmaceutical company agreed to sell a Rare Pediatric Disease Priority Review Voucher for $210 million. The voucher was awarded to Ultragenyx after the US Food and Drug Administration approved GENGLYCOS, also known as DTX401, for glycogen storage disease (GSD) type Ia.
- 2026-10-07 Ultragenyx Enters into Agreement to Sell Rare Pediatric Disease Priority Review Voucher for $210 Million NOVATO, Calif., Oct. 07, 2026 (GLOBE NEWSWIRE) -- Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE) today announced that it has entered into a definitive agreement to sell a Rare Pediatric Disease Priority Review Voucher (PRV) for $210 million. Ultragenyx received the PRV upon U.S. Food and Drug Administration (FDA) approval of GENGLYCOS™ (pariglasgene brecaparvovec-opnr), also known as DTX401, the first treatment designed to address the underlying cause of glycogen storage disease type Ia (GSDIa).
- 2026-10-06 INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Ultragenyx Pharmaceutical Inc. - RARE NEW YORK, Oct. 06, 2026 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of Ultragenyx Pharmaceutical Inc. (“Ultragenyx” or the “Company”) (NASDAQ: RARE). Such investors are advised to contact Danielle Peyton at [email protected] or 646-581-9980, ext. 7980.
Market snapshot
Financial ratios
| Metric | Trend | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|---|
| Gross Profit Margin | 83.8% | 86.3% | 89.6% | 92.2% | 95.4% | |
| Ebit Margin | -75.6% | -90.1% | -124.9% | -181.3% | -120.5% | |
| Ebitda Margin | -70.4% | -83.7% | -118.9% | -176.3% | -116.8% | |
| Operating Profit Margin | -79.5% | -95.7% | -131.1% | -178.6% | -108.6% | |
| Pretax Profit Margin | -84.8% | -101.3% | -140.1% | -193.1% | -128.9% | |
| Continuous Operations Profit Margin | -85.4% | -101.6% | -139.7% | -194.7% | -129.2% | |
| Net Profit Margin | -85.4% | -101.6% | -139.7% | -194.7% | -129.2% | |
| Bottom Line Profit Margin | -85.4% | -101.6% | -139.7% | -194.7% | -129.2% | |
| Current Ratio | 2.477 | 2.374 | 2.611 | 3.384 | 4.723 | |
| Quick Ratio | 2.341 | 2.244 | 2.490 | 3.281 | 4.634 | |
| Solvency Ratio | -0.336 | -0.430 | -0.478 | -0.578 | -0.735 | |
| Cash Ratio | 1.130 | 0.505 | 0.762 | 0.509 | 1.696 | |
| Price To Earnings Ratio | -3.945 | -6.688 | -5.796 | -4.578 | -12.551 | |
| Price To Earnings Growth Ratio | 0.539 | 0.282 | 0.314 | -0.090 | -0.106 | |
| Forward Price To Earnings Growth Ratio | 0.539 | 0.282 | 0.314 | -0.090 | -0.106 | |
| Price To Earnings Diluted Ratio | -3.945 | -6.688 | -5.796 | -4.578 | -12.551 | |
| Price To Earnings Diluted Growth Ratio | 0.539 | 0.282 | 0.314 | -0.090 | -0.106 | |
| Price To Book Ratio | -28.348 | 14.920 | 12.769 | 9.189 | 6.179 | |
| Price To Sales Ratio | 3.370 | 6.799 | 8.099 | 8.915 | 16.223 | |
| Price To Free Cash Flow Ratio | -4.805 | -9.033 | -6.743 | -6.151 | -13.844 | |
| Price To Operating Cash Flow Ratio | -4.867 | -9.196 | -7.407 | -8.514 | -16.832 | |
| Debt To Assets Ratio | 0.833 | 0.027 | 0.029 | 0.020 | 0.028 | |
| Debt To Equity Ratio | -15.950 | 0.158 | 0.157 | 0.090 | 0.045 | |
| Debt To Capital Ratio | 1.067 | 0.136 | 0.136 | 0.082 | 0.044 | |
| Long Term Debt To Capital Ratio | 1.073 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Financial Leverage Ratio | -19.150 | 5.889 | 5.414 | 4.384 | 1.650 | |
| Working Capital Turnover Ratio | 1.294 | 1.212 | 0.808 | 0.560 | 0.395 | |
| Operating Cash Flow Ratio | -1.214 | -1.203 | -1.693 | -1.457 | -1.867 | |
| Operating Cash Flow Sales Ratio | -0.692 | -0.739 | -1.093 | -1.047 | -0.964 | |
| Free Cash Flow Operating Cash Flow Ratio | 1.013 | 1.018 | 1.098 | 1.384 | 1.216 | |
| Debt Service Coverage Ratio | -3.343 | -7.465 | -7.797 | -15.022 | -13.982 | |
| Interest Coverage Ratio | -8.629 | -8.502 | -8.624 | -15.086 | -12.975 | |
| Short Term Operating Cash Flow Coverage Ratio | -5.753 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Operating Cash Flow Coverage Ratio | -0.365 | -10.268 | -10.999 | -12.043 | -8.070 | |
| Capital Expenditure Coverage Ratio | -77.667 | -55.291 | -10.153 | -2.604 | -4.634 | |
| Dividend Paid And Capex Coverage Ratio | -77.667 | -55.291 | -10.153 | -2.604 | -4.634 | |
| Dividend Payout Ratio | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Enterprise Value Multiple | -6.561 | -7.837 | -6.480 | -4.899 | -13.247 |
Sparkline shows each ratio oldest → newest (left → right).
How the latest year compares
For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower
| Metric | Current | vs 1Y ago | vs 5Y avg |
|---|---|---|---|
| Gross Profit Margin | 83.8% | ▼-2.5% | ▼-5.7% |
| Ebit Margin | -75.6% | ▲14.4% | ▲42.9% |
| Ebitda Margin | -70.4% | ▲13.3% | ▲42.8% |
| Operating Profit Margin | -79.5% | ▲16.2% | ▲39.2% |
| Pretax Profit Margin | -84.8% | ▲16.5% | ▲44.8% |
| Continuous Operations Profit Margin | -85.4% | ▲16.2% | ▲44.7% |
| Net Profit Margin | -85.4% | ▲16.2% | ▲44.7% |
| Bottom Line Profit Margin | -85.4% | ▲16.2% | ▲44.7% |
| Current Ratio | 2.477 | ▲0.102 | ▼-0.637 |
| Quick Ratio | 2.341 | ▲0.098 | ▼-0.657 |
| Solvency Ratio | -0.336 | ▲0.093 | ▲0.175 |
| Cash Ratio | 1.130 | ▲0.625 | ▲0.210 |
| Price To Earnings Ratio | -3.945 | ▲2.743 | ▲2.767 |
| Price To Earnings Growth Ratio | 0.539 | ▲0.258 | ▲0.352 |
| Forward Price To Earnings Growth Ratio | 0.539 | ▲0.258 | ▲0.352 |
| Price To Earnings Diluted Ratio | -3.945 | ▲2.743 | ▲2.767 |
| Price To Earnings Diluted Growth Ratio | 0.539 | ▲0.258 | ▲0.352 |
| Price To Book Ratio | -28.348 | ▼-43.267 | ▼-31.290 |
| Price To Sales Ratio | 3.370 | ▼-3.429 | ▼-5.311 |
| Price To Free Cash Flow Ratio | -4.805 | ▲4.228 | ▲3.311 |
| Price To Operating Cash Flow Ratio | -4.867 | ▲4.330 | ▲4.497 |
| Debt To Assets Ratio | 0.833 | ▲0.806 | ▲0.646 |
| Debt To Equity Ratio | -15.950 | ▼-16.108 | ▼-12.850 |
| Debt To Capital Ratio | 1.067 | ▲0.930 | ▲0.774 |
| Long Term Debt To Capital Ratio | 1.073 | ▲1.073 | ▲0.859 |
| Financial Leverage Ratio | -19.150 | ▼-25.039 | ▼-18.788 |
| Working Capital Turnover Ratio | 1.294 | ▲0.083 | ▲0.441 |
| Operating Cash Flow Ratio | -1.214 | ▼-0.010 | ▲0.273 |
| Operating Cash Flow Sales Ratio | -0.692 | ▲0.047 | ▲0.215 |
| Free Cash Flow Operating Cash Flow Ratio | 1.013 | ▼-0.005 | ▼-0.133 |
| Debt Service Coverage Ratio | -3.343 | ▲4.122 | ▲6.179 |
| Interest Coverage Ratio | -8.629 | ▼-0.127 | ▲2.134 |
| Short Term Operating Cash Flow Coverage Ratio | -5.753 | ▼-5.753 | ▼-4.603 |
| Operating Cash Flow Coverage Ratio | -0.365 | ▲9.902 | ▲7.984 |
| Capital Expenditure Coverage Ratio | -77.667 | ▼-22.375 | ▼-47.597 |
| Dividend Paid And Capex Coverage Ratio | -77.667 | ▼-22.375 | ▼-47.597 |
| Dividend Payout Ratio | 0.000 | 0.000 | 0.000 |
| Enterprise Value Multiple | -6.561 | ▲1.276 | ▲1.244 |
Key metrics
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Market cap | $2.27B | $3.81B | $3.52B | $3.24B | $5.70B | |
| Enterprise value | $3.11B | $3.68B | $3.35B | $3.14B | $5.44B | |
| EV / Sales | 4.62x | 6.56x | 7.71x | 8.64x | 15.47x | |
| EV / Op. cash flow | -6.67x | -8.87x | -7.05x | -8.25x | -16.05x | |
| EV / Free cash flow | -6.59x | -8.72x | -6.42x | -5.96x | -13.20x | |
| EV / EBITDA | -6.56x | -7.84x | -6.48x | -4.90x | -13.25x | |
| Net debt / EBITDA | -1.78x | 0.28x | 0.33x | 0.16x | 0.65x | |
| Current ratio | 2.48x | 2.37x | 2.61x | 3.38x | 4.72x | |
| Income quality | 0.81x | 0.73x | 0.78x | 0.54x | 0.75x | |
| Graham net-net | -$8 | -$6 | -$8 | -$6 | $3 | |
| Tax burden | 100.7% | 100.3% | 99.7% | 100.8% | 100.2% | |
| Interest burden | 112.2% | 112.5% | 112.2% | 106.5% | 106.9% | |
| Working capital | $567.0M | $473.0M | $451.7M | $622.7M | $675.2M | |
| Invested capital | $1.05B | $961.6M | $953.0M | $1.09B | $1.03B | |
| Return on assets | -37.5% | -37.9% | -40.7% | -45.8% | -29.8% | |
| Operating ROA | -35.3% | -35.8% | -37.5% | -42.3% | -23.3% | |
| Return on tangible assets | -43.8% | -44.4% | -47.4% | -52.8% | -33.7% | |
| Return on equity | 718.8% | -222.9% | -220.3% | -200.7% | -49.2% | |
| Return on invested capital | -43.5% | -45.8% | -46.4% | -50.1% | -28.2% | |
| Return on capital employed | -46.6% | -46.2% | -47.0% | -50.5% | -28.5% | |
| Earnings yield | -25.4% | -14.9% | -17.2% | -21.8% | -8.0% | |
| Free cash flow yield | -20.8% | -11.1% | -14.8% | -16.3% | -7.2% | |
| Capex / Op. cash flow | -1.3% | -1.8% | -9.8% | -38.4% | -21.6% | |
| Capex / Depreciation | 17.1% | 21.1% | 179.8% | 802.0% | 552.1% | |
| Capex / Sales | 0.9% | 1.3% | 10.8% | 40.2% | 20.8% | |
| SG&A / Sales | 51.9% | 57.4% | 71.3% | 76.6% | 62.6% | |
| R&D / Sales | 111.4% | 124.6% | 149.3% | 194.3% | 141.5% | |
| Stock comp / Sales | 22.7% | 28.2% | 31.1% | 35.9% | 29.9% | |
| Intangibles / Total assets | 14.4% | 14.8% | 14.1% | 13.2% | 11.5% | |
| Days sales outstanding | 86d | 79d | 62d | 41d | 46d | |
| Days payables outstanding | 104d | 184d | 340d | 558d | 391d | |
| Operating cycle | 260d | 293d | 336d | 386d | 416d | |
| Cash conversion cycle | 157d | 109d | -4d | -172d | 25d |
Change by theme
Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.
Change over 1 year
Change over 5 years