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CRL

Neutral signalScored 2026-10-26 Drivers: Congress, trend, fundamentals. Moteurs : Congrès, tendance, fondamentaux.

Research, not advice.

À propos

Charles River Laboratories International, Inc.

Nom
Charles River Laboratories International, Inc.
Secteur
Healthcare
Industrie
Medical - Diagnostics & Research
Bourse
NYSE
Capitalisation
$16.6B
Employés
19,000
PDG
Birgit Girshick
Site web
https://www.criver.com
Marché
CERTGNNSFHNGZYICLRMEDPWUXIF

Charles River Laboratories International, Inc. operates as a contract research organization (CRO), providing essential preclinical services to the pharmaceutical and biotechnology industries. Its core business revolves around assisting clients with drug discovery, non-clinical development, and thorough safety testing, with its services extending globally across the United States, Europe, Canada, and the Asia Pacific region. The company organizes its diverse offerings into three principal segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. 1. Research Models and Services (RMS): This division is a key supplier of high-quality rodent research models, including specially bred strains of rats and mice for experimental purposes. It also offers a comprehensive array of support services to help clients effectively utilize these models in their research and for the screening of potential non-clinical drug candidates. These include providing genetically engineered models, insourcing solutions for facility management, and diagnostic services for research animals. 2. Discovery and Safety Assessment (DSA): The DSA segment plays a crucial role in advancing early-stage drug pipelines. It delivers early-phase and in vivo discovery services focused on identifying and validating new therapeutic targets, chemical compounds, and antibodies. The ultimate goal is to prepare promising non-clinical drug and therapeutic candidates for subsequent safety evaluations. Additionally, this segment provides an extensive range of safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism studies, and pharmacokinetics. 3. Manufacturing Solutions: This segment addresses critical quality control requirements by offering in vitro methods for both routine and rapid testing of the quality of sterile and non-sterile pharmaceuticals, as well as consumer products. It also serves as a vital provider of specialized biologics testing, which is often outsourced by pharmaceutical and biotechnology companies. Furthermore, the segment supplies avian vaccine services, including specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products, all essential for vaccine production. Beyond these specialized segments, Charles River also manages contract vivarium operations, providing crucial animal housing and care facilities for its biopharmaceutical clients. The company was founded in 1947 and is headquartered in Wilmington, Massachusetts.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

VENTE TOTALE: 24 042 titres (~8 414 700,00 $ US)

Insiders
FOSTER JAMES C
Total bought
—

Avg buy (VWAP, 90d window) $297.43 vs last close $357.27 (+20.1%)

Total sold
$25,174,103

Avg sell (VWAP, 90d window) $286.19 vs last close $357.27 (+24.8%)

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

$23,057,271 of that total is under a Rule 10b5-1 plan. It is shown here and left out of the score.

Last activity
2026-10-22
Liquidity
Liquid $394,459,199/day · 20d vol
Last synced
2026-10-26 22:35:44 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-10-21 Parisotto Shannon M Sell · S 2,156 $344.41 $742,548 Form 4
2026-10-05 Parisotto Shannon M Sell · S · 10b5-1 981 $308.44 $302,580 Form 4
2026-09-30 Coleman Glenn Buy · P 10 $297.43 $2,974 Form 4
2026-08-25 FOSTER JAMES C Sell · S · 10b5-1 33,561 $300.00 $10,068,300 Form 4
2026-08-19 Parisotto Shannon M Sell · S · 10b5-1 2,039 $294.12 $599,711 Form 4
2026-08-18 Andrews Nancy C Sell · S 573 $285.24 $163,443 Form 4
2026-08-11 Girshick Birgit Sell · S · 10b5-1 6,500 $279.90 $1,819,350 Form 4
2026-08-11 Parisotto Shannon M Sell · S · 10b5-1 3,714 $279.66 $1,038,657 Form 4
2026-08-10 FOSTER JAMES C Sell · S · 10b5-1 28,733 $275.00 $7,901,575 Form 4
2026-08-06 Creamer Victoria L Sell · S 4,179 $259.16 $1,083,030 Form 4
2026-08-06 Knell Michael Gunnar Sell · S 482 $265.17 $127,812 Form 4
2026-08-05 Parisotto Shannon M Sell · S · 10b5-1 5,046 $263.00 $1,327,098 Form 4

Sales marked 10b5-1 are scheduled in advance and don't count toward the Quorum score. Les ventes marquées 10b5-1 sont planifiées à l'avance et ne pèsent pas dans le score Quorum.

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Recent trades

DateRepresentativeTypeAmount
2025-05-15Robert P. BresnahanSale (Full)$1,001 - $15,000
2025-05-12Jefferson ShreveSale (Full)$15,001 - $50,000
2025-05-08Jefferson ShrevePurchase$15,001 - $50,000
2025-04-08Robert P. BresnahanPurchase$15,001 - $50,000
2025-01-15Julie JohnsonPurchase$1,001 - $15,000
2024-11-15Ro KhannaPurchase$1,001 - $15,000
2023-11-03Ro KhannaSale$1,001 - $15,000
2023-10-02Ro KhannaPurchase$1,001 - $15,000
2023-09-08Lois FrankelSale (Full)$1,001 - $15,000
2023-08-29Ro KhannaSale$1,001 - $15,000
2023-05-23Ro KhannaPurchase$1,001 - $15,000
2023-05-19Ro KhannaPurchase$1,001 - $15,000
2023-04-25Lois FrankelPurchase$1,001 - $15,000
2022-08-25Zoe LofgrenSale (Full)$1,001 - $15,000
2022-06-16Ro KhannaSale$1,001 - $15,000
2022-05-23Ro KhannaPurchase$1,001 - $15,000
2022-05-10Ro KhannaSale$1,001 - $15,000
2022-05-05Ro KhannaPurchase$1,001 - $15,000
2022-02-17Ro KhannaSale$1,001 - $15,000
2022-01-21Ro KhannaPurchase$1,001 - $15,000
2022-01-20Ro KhannaSale$1,001 - $15,000
2022-01-11Ro KhannaPurchase$1,001 - $15,000
2021-09-30Zoe LofgrenPurchase$1,001 - $15,000
2019-10-08Susie LeeSale (Full)$1,001 - $15,000
2019-10-07Susie LeeSale (Partial)$1,001 - $15,000
2019-08-29Susie LeePurchase$1,001 - $15,000
2019-06-24Donna ShalalaSale (Full)$1,001 - $15,000
2018-09-26Lamar Seeligson SmithSale (Full)$1,001 - $15,000
2018-09-19Thomas Charles MacArthurPurchase$1,001 - $15,000
2018-09-13Thomas Charles MacArthurPurchase$1,001 - $15,000
2018-09-12Thomas Charles MacArthurPurchase$1,001 - $15,000
2018-09-11Thomas Charles MacArthurPurchase$1,001 - $15,000
2018-07-26Lamar Seeligson SmithSale (Partial)$1,001 - $15,000

Signal

Neutral signalScored 2026-10-26 Drivers: Congress, trend, fundamentals. Moteurs : Congrès, tendance, fondamentaux.

CRL presents a deeply deteriorated fundamental profile — net losses in 2025, a debt-to-EBITDA of 6.94x, and declining interest coverage — that materially undermines the moderate catalyst score of 55.

The first sentence of the analysis written for CRL on 2026-10-26 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Neutral signal Drivers: Congress, trend, fundamentals. Moteurs : Congrès, tendance, fondamentaux.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Pulls against a bullish reading. Selling cluster — sale value, no purchase value
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Congress Supports a bullish reading. 3 purchase disclosures year to date
  • Timing Supports a bullish reading. Interesting trend — weekly bias up
  • Financial indicators Supports a bullish reading. Current ratio 1.29 · operating margin 13%

Suggested stop 260.56, nearest stored support minus 0.5 ATR(27.1% under the last close). Research, not advice. Not an order.

Recent news

Market snapshot

Financial ratios

MetricTrend2025-12-272024-12-282023-12-312022-12-312021-12-31
Gross Profit Margin30.5%32.9%36.4%36.8%37.7%
Ebit Margin0.2%5.4%17.4%17.2%15.7%
Ebitda Margin10.2%14.3%25.0%24.8%23.2%
Operating Profit Margin12.6%5.6%14.9%16.4%16.7%
Pretax Profit Margin-2.5%2.3%14.1%15.7%13.6%
Continuous Operations Profit Margin-3.5%0.6%11.6%12.4%11.3%
Net Profit Margin-3.6%0.3%11.5%12.2%11.0%
Bottom Line Profit Margin-3.6%0.3%11.5%12.2%11.0%
Current Ratio1.2921.4111.5251.3181.233
Quick Ratio1.0251.1311.1641.0841.040
Solvency Ratio0.0660.0930.1740.1730.148
Cash Ratio0.1910.1960.2620.2140.237
Price To Earnings Ratio-69.986930.80025.50222.76948.492
Price To Earnings Growth Ratio0.045-9.513-8.1350.9838.486
Forward Price To Earnings Growth Ratio0.045-9.513-8.1350.9838.486
Price To Earnings Diluted Ratio-69.986930.80025.64022.98549.576
Price To Earnings Diluted Growth Ratio0.045-9.514-9.3490.9298.924
Price To Book Ratio3.1902.7633.3673.7207.476
Price To Sales Ratio2.5142.3622.9332.7855.353
Price To Free Cash Flow Ratio19.46819.06833.14537.54435.617
Price To Operating Cash Flow Ratio13.68413.02117.70717.86824.907
Debt To Assets Ratio0.4300.3620.3740.4070.456
Debt To Equity Ratio0.9690.7870.8531.0411.265
Debt To Capital Ratio0.4920.4400.4600.5100.558
Long Term Debt To Capital Ratio0.4460.3930.4240.4760.535
Financial Leverage Ratio2.2552.1752.2782.5542.771
Working Capital Turnover Ratio10.9168.4159.16613.51611.756
Operating Cash Flow Ratio0.6580.7390.6480.5680.736
Operating Cash Flow Sales Ratio0.1840.1810.1660.1560.215
Free Cash Flow Operating Cash Flow Ratio0.7030.6830.5340.4760.699
Debt Service Coverage Ratio2.1904.0656.81214.4339.975
Interest Coverage Ratio4.7451.8004.51510.9797.981
Short Term Operating Cash Flow Coverage Ratio12.0810.0000.0000.0007,532.663
Operating Cash Flow Coverage Ratio0.2410.2700.2230.2000.237
Capital Expenditure Coverage Ratio3.3663.1532.1471.9083.326
Dividend Paid And Capex Coverage Ratio3.3663.1532.1471.9083.326
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple31.51120.81114.43614.13126.714

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 30.5% ▼-2.4% ▼-4.3%
Ebit Margin 0.2% ▼-5.2% ▼-11.0%
Ebitda Margin 10.2% ▼-4.1% ▼-9.3%
Operating Profit Margin 12.7% ▲7.0% ▼-0.6%
Pretax Profit Margin -2.5% ▼-4.8% ▼-11.1%
Continuous Operations Profit Margin -3.5% ▼-4.2% ▼-10.0%
Net Profit Margin -3.6% ▼-3.9% ▼-9.9%
Bottom Line Profit Margin -3.6% ▼-3.9% ▼-9.9%
Current Ratio 1.292 ▼-0.120 ▼-0.064
Quick Ratio 1.025 ▼-0.106 ▼-0.064
Solvency Ratio 0.066 ▼-0.026 ▼-0.065
Cash Ratio 0.191 ▼-0.005 ▼-0.029
Price To Earnings Ratio -69.986 ▼-1000.786 ▼-261.502
Price To Earnings Growth Ratio 0.045 ▲9.558 ▲1.672
Forward Price To Earnings Growth Ratio 0.045 ▲9.558 ▲1.672
Price To Earnings Diluted Ratio -69.986 ▼-1000.786 ▼-261.789
Price To Earnings Diluted Growth Ratio 0.045 ▲9.559 ▲1.838
Price To Book Ratio 3.190 ▲0.426 ▼-0.913
Price To Sales Ratio 2.514 ▲0.152 ▼-0.675
Price To Free Cash Flow Ratio 19.468 ▲0.400 ▼-9.500
Price To Operating Cash Flow Ratio 13.684 ▲0.663 ▼-3.753
Debt To Assets Ratio 0.430 ▲0.068 ▲0.024
Debt To Equity Ratio 0.969 ▲0.182 ▼-0.014
Debt To Capital Ratio 0.492 ▲0.052 ▼-0.000
Long Term Debt To Capital Ratio 0.446 ▲0.053 ▼-0.009
Financial Leverage Ratio 2.255 ▲0.080 ▼-0.152
Working Capital Turnover Ratio 10.916 ▲2.501 ▲0.162
Operating Cash Flow Ratio 0.658 ▼-0.081 ▼-0.011
Operating Cash Flow Sales Ratio 0.184 ▲0.002 ▲0.003
Free Cash Flow Operating Cash Flow Ratio 0.703 ▲0.020 ▲0.084
Debt Service Coverage Ratio 2.190 ▼-1.874 ▼-5.305
Interest Coverage Ratio 4.745 ▲2.945 ▼-1.259
Short Term Operating Cash Flow Coverage Ratio 12.081 ▲12.081 ▼-1496.868
Operating Cash Flow Coverage Ratio 0.241 ▼-0.029 ▲0.006
Capital Expenditure Coverage Ratio 3.366 ▲0.213 ▲0.586
Dividend Paid And Capex Coverage Ratio 3.366 ▲0.213 ▲0.586
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple 31.511 ▲10.700 ▲9.990

Key metrics

MetricTrend20252024202320222021
Market cap$10.09B$9.56B$12.11B$11.07B$18.95B
Enterprise value$12.95B$12.09B$14.90B$13.94B$21.91B
EV / Sales3.22x2.99x3.61x3.50x6.19x
EV / Op. cash flow17.55x16.46x21.79x22.49x28.80x
EV / Free cash flow24.97x24.11x40.78x47.25x41.18x
EV / EBITDA31.51x20.81x14.44x14.13x26.71x
Net debt / EBITDA6.94x4.35x2.70x2.90x3.61x
Current ratio1.29x1.41x1.52x1.32x1.23x
Income quality-5.19x29.05x1.42x1.26x1.91x
Graham number—$17$121$112$94
Graham net-net-$61-$61-$68-$72-$72
Tax burden145.1%11.1%81.7%78.0%81.3%
Interest burden-1322.1%42.4%81.0%91.3%86.7%
Working capital$326.7M$409.0M$553.6M$347.4M$240.9M
Invested capital$5.45B$6.00B$6.55B$6.01B$5.60B
Return on assets-2.0%0.1%5.8%6.4%5.6%
Operating ROA6.9%2.9%7.8%8.9%9.4%
Return on tangible assets-3.6%0.3%11.2%12.8%12.0%
Return on equity-4.6%0.3%13.2%16.3%15.4%
Return on invested capital8.4%0.9%7.1%7.9%8.1%
Return on capital employed8.4%3.5%8.6%10.0%9.8%
Earnings yield-1.4%0.1%3.9%4.4%2.1%
Free cash flow yield5.1%5.2%3.0%2.7%2.8%
Capex / Op. cash flow29.7%31.7%46.6%52.4%30.1%
Capex / Depreciation54.3%64.4%101.4%106.9%86.2%
Capex / Sales5.5%5.8%7.7%8.2%6.5%
SG&A / Sales18.5%18.5%18.1%16.7%17.5%
R&D / Sales0.0%0.0%0.0%0.0%0.0%
Stock comp / Sales1.8%1.7%1.7%1.9%2.0%
Intangibles / Total assets43.5%47.4%48.3%50.0%53.7%
Days sales outstanding64d65d69d69d67d
Days payables outstanding19d19d23d30d33d
Operating cycle104d102d122d106d100d
Cash conversion cycle84d84d98d76d67d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▲+5.5%EV / Sales ▲+8.0%EV / EBITDA ▲+51.4%EV / Op. cash flow ▲+1.086Earnings yield ▼-0.015
Profitability
Return on equity ▼-0.049Return on assets ▼-0.022Return on invested capital ▲+0.074Return on capital employed ▲+0.050Operating ROA ▲+0.040Income quality ▼-34.234Tax burden ▲+1.340
Efficiency
Days sales outstanding ▼-0.536Days payables outstanding ▲+0.623Operating cycle ▲+1.193Cash conversion cycle ▲+0.570Capex / Sales ▼-0.003R&D / Sales n/a
Balance-sheet strength
Current ratio ▼-0.120Net debt / EBITDA ▲+2.589Working capital ▼-82236000.000Invested capital ▼-547866000.000Intangibles / Total assets ▼-0.039

Change over 5 years

Valuation
Market cap ▼-46.7%EV / Sales ▼-47.9%EV / EBITDA ▲+18.0%EV / Op. cash flow ▼-11.248Earnings yield ▼-0.035
Profitability
Return on equity ▼-0.200Return on assets ▼-0.076Return on invested capital ▲+0.002Return on capital employed ▼-0.014Operating ROA ▼-0.025Income quality ▼-7.096Tax burden ▲+0.637
Efficiency
Days sales outstanding ▼-2.621Days payables outstanding ▼-13.321Operating cycle ▲+3.555Cash conversion cycle ▲+16.876Capex / Sales ▼-0.010R&D / Sales n/a
Balance-sheet strength
Current ratio ▲+0.058Net debt / EBITDA ▲+3.332Working capital ▲+85824000.000Invested capital ▼-150376000.000Intangibles / Total assets ▼-0.102

Employee count

Peer market caps