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XFOR

Bearish signalScored 2026-08-16 Drivers: fundamentals. Moteurs : fondamentaux.

Research, not advice.

À propos

X4 Pharmaceuticals, Inc.

Nom
X4 Pharmaceuticals, Inc.
Secteur
Healthcare
Industrie
Biotechnology
Bourse
NASDAQ
Capitalisation
$322.2M
Employés
45
PDG
Adam R. Craig
Site web
https://www.x4pharma.com
Marché
ALGSFGENINMBKPTIKZRMRSN

X4 Pharmaceuticals, Inc. is a biopharmaceutical firm committed to the discovery, development, and commercialization of innovative therapies for uncommon immune system disorders. Its primary drug candidate, XOLREMDI (also known as mavorixafor), is an orally administered, small-molecule antagonist specifically designed to target the chemokine receptor CXCR4. This compound is currently undergoing Phase 3 clinical trials for the management of WHIM syndrome, a rare immunodeficiency characterized by symptoms such as warts, hypogammaglobulinemia, recurrent infections, and myelokathexis. To broaden its global presence, the company has entered into several licensing agreements: A partnership with Abbisko Therapeutics Co Ltd. grants rights for the manufacturing and distribution of XOLREMDI in mainland China, Taiwan, Hong Kong, and Macau. Another agreement with Norgine covers the development, production, and commercialization of mavorixafor across Europe, Australia, and New Zealand. Furthermore, X4 Pharmaceuticals holds a comprehensive agreement with Genzyme Corporation concerning the CXCR4 receptor, allowing for the development and commercialization of licensed compounds for all medical applications, including therapeutic, preventive, and diagnostic uses. The company maintains its corporate headquarters in Boston, Massachusetts.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

VENTE TOTALE: 47 436 titres (~210 829,30 $ US)

Insiders
Craig Adam R
Total bought
—

Avg buy (VWAP, 90d window) $2.58 vs last close —

Total sold
$353,716

Avg sell (VWAP, 90d window) $4.22 vs last close —

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

Last activity
2026-08-12
Last synced
2026-08-21 23:36:53 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-10-16 Craig Adam R Buy · P 4,600 $2.58 $11,884 Form 4
2026-10-01 KIRSKE DAVID Sell · S 11,767 $2.86 $33,658 Form 4
2026-08-12 Craig Adam R Sell · S 47,436 $4.44 $210,829 Form 4
2026-08-12 Volpone John Sell · S 24,576 $4.44 $109,228 Form 4

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Signal

Bearish signalScored 2026-08-16 Drivers: fundamentals. Moteurs : fondamentaux.

XFOR presents a deeply conflicted profile: while short-term liquidity is adequate (75) and a Zacks Rank #2 upgrade provides a moderate catalyst signal (55), the fundamental health score of 25 reflects severe structural…

The first sentence of the analysis written for XFOR on 2026-08-16 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Bearish signal Drivers: fundamentals. Moteurs : fondamentaux.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Pulls against a bullish reading. Selling cluster — sale value, no purchase value
  • Congress Unavailable or mixed. No purchase disclosures in the stored window
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Timing Unavailable or mixed. No stored price series
  • Financial indicators Unavailable or mixed. Current ratio 10.16 · operating margin -247% — readings disagree

Market snapshot

Financial ratios

MetricTrend2025-12-312024-12-312023-12-312022-12-312021-12-31
Gross Profit Margin82.2%68.8%0.0%0.0%0.0%
Ebit Margin-200.2%-1109.6%0.0%0.0%0.0%
Ebitda Margin-196.5%-1078.5%0.0%0.0%0.0%
Operating Profit Margin-247.4%-1423.6%0.0%0.0%0.0%
Pretax Profit Margin-225.4%-1452.5%0.0%0.0%0.0%
Continuous Operations Profit Margin-225.6%-1464.6%0.0%0.0%0.0%
Net Profit Margin-225.6%-1464.6%0.0%0.0%0.0%
Bottom Line Profit Margin-225.6%-1464.6%0.0%0.0%0.0%
Current Ratio10.1563.4125.3405.7646.267
Quick Ratio9.9823.3265.3405.7646.267
Solvency Ratio-0.748-0.295-1.048-1.145-1.645
Cash Ratio8.4271.6944.3405.4525.832
Price To Earnings Ratio-2.139-3.937-1.474-0.653-0.575
Price To Earnings Growth Ratio0.0320.0590.0240.011-0.020
Forward Price To Earnings Growth Ratio0.0320.0590.0240.011-0.020
Price To Earnings Diluted Ratio-2.139-3.937-1.474-0.653-0.575
Price To Earnings Diluted Growth Ratio0.0320.0590.0240.011-0.020
Price To Book Ratio0.9086.6602.9180.8520.915
Price To Sales Ratio4.81857.6900.0000.0000.000
Price To Free Cash Flow Ratio-1.909-1.067-1.544-0.817-0.824
Price To Operating Cash Flow Ratio-1.976-1.127-1.545-0.818-0.832
Debt To Assets Ratio0.2660.5330.3960.2470.340
Debt To Equity Ratio0.4153.5251.1410.5190.618
Debt To Capital Ratio0.2930.7790.5330.3420.382
Long Term Debt To Capital Ratio0.2910.7730.5160.3040.340
Financial Leverage Ratio1.5596.6122.8822.1011.819
Working Capital Turnover Ratio0.2230.0290.0000.0000.000
Operating Cash Flow Ratio-3.324-3.982-4.222-3.454-5.056
Operating Cash Flow Sales Ratio-2.438-51.1930.0000.0000.000
Free Cash Flow Operating Cash Flow Ratio1.0351.0561.0011.0011.009
Debt Service Coverage Ratio-7.779-3.180-16.440-16.835-15.087
Interest Coverage Ratio-9.789-4.152-18.612-21.931-20.689
Short Term Operating Cash Flow Coverage Ratio0.0000.0000.000-58.633-37.917
Operating Cash Flow Coverage Ratio-1.108-1.676-1.656-2.007-1.782
Capital Expenditure Coverage Ratio-28.539-17.868-1,608.533-748.563-115.293
Dividend Paid And Capex Coverage Ratio-28.539-17.868-1,608.533-748.563-115.293
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple-0.426-6.161-1.1400.226-0.204

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 82.2% ▲13.4% ▲52.0%
Ebit Margin -200.2% ▲909.4% ▲61.8%
Ebitda Margin -196.5% ▲881.9% ▲58.5%
Operating Profit Margin -247.4% ▲1176.1% ▲86.8%
Pretax Profit Margin -225.4% ▲1227.0% ▲110.1%
Continuous Operations Profit Margin -225.6% ▲1239.0% ▲112.5%
Net Profit Margin -225.6% ▲1239.0% ▲112.5%
Bottom Line Profit Margin -225.6% ▲1239.0% ▲112.5%
Current Ratio 10.156 ▲6.744 ▲3.968
Quick Ratio 9.982 ▲6.655 ▲3.846
Solvency Ratio -0.748 ▼-0.453 ▲0.228
Cash Ratio 8.427 ▲6.733 ▲3.278
Price To Earnings Ratio -2.139 ▲1.798 ▼-0.383
Price To Earnings Growth Ratio 0.032 ▼-0.026 ▲0.011
Forward Price To Earnings Growth Ratio 0.032 ▼-0.026 ▲0.011
Price To Earnings Diluted Ratio -2.139 ▲1.798 ▼-0.383
Price To Earnings Diluted Growth Ratio 0.032 ▼-0.026 ▲0.011
Price To Book Ratio 0.908 ▼-5.752 ▼-1.543
Price To Sales Ratio 4.818 ▼-52.872 ▼-7.684
Price To Free Cash Flow Ratio -1.909 ▼-0.842 ▼-0.677
Price To Operating Cash Flow Ratio -1.976 ▼-0.849 ▼-0.716
Debt To Assets Ratio 0.266 ▼-0.267 ▼-0.090
Debt To Equity Ratio 0.415 ▼-3.111 ▼-0.829
Debt To Capital Ratio 0.293 ▼-0.486 ▼-0.172
Long Term Debt To Capital Ratio 0.290 ▼-0.482 ▼-0.154
Financial Leverage Ratio 1.559 ▼-5.053 ▼-1.435
Working Capital Turnover Ratio 0.223 ▲0.194 ▲0.173
Operating Cash Flow Ratio -3.324 ▲0.657 ▲0.683
Operating Cash Flow Sales Ratio -2.438 ▲48.755 ▲8.288
Free Cash Flow Operating Cash Flow Ratio 1.035 ▼-0.021 ▲0.015
Debt Service Coverage Ratio -7.779 ▼-4.598 ▲4.085
Interest Coverage Ratio -9.789 ▼-5.637 ▲5.246
Short Term Operating Cash Flow Coverage Ratio 0.000 0.000 ▲19.310
Operating Cash Flow Coverage Ratio -1.108 ▲0.569 ▲0.538
Capital Expenditure Coverage Ratio -28.539 ▼-10.671 ▲475.220
Dividend Paid And Capex Coverage Ratio -28.539 ▼-10.671 ▲475.220
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple -0.426 ▲5.735 ▲1.115

Key metrics

MetricTrend20252024202320222021
Market cap$169.2M$147.5M$149.1M$63.1M$59.0M
Enterprise value$29.4M$169.9M$108.2M-$20.2M$17.0M
EV / Sales0.84x66.44x0.00x0.00x0.00x
EV / Op. cash flow-0.34x-1.30x-1.12x0.26x-0.24x
EV / Free cash flow-0.33x-1.23x-1.12x0.26x-0.24x
EV / EBITDA-0.43x-6.16x-1.14x0.23x-0.20x
Net debt / EBITDA2.02x-0.81x0.43x0.93x0.51x
Current ratio10.16x3.41x5.34x5.76x6.27x
Income quality1.08x3.50x0.95x0.82x0.80x
Graham net-net$4-$3$3$19$34
Tax burden100.1%100.8%100.1%100.0%100.0%
Interest burden112.6%130.9%106.1%104.4%104.3%
Working capital$235.8M$79.3M$99.2M$106.4M$73.9M
Invested capital$264.0M$111.5M$123.0M$132.0M$101.4M
Return on assets-27.3%-25.6%-68.7%-60.3%-75.7%
Operating ROA-39.8%-24.8%-71.0%-64.2%-62.8%
Return on tangible assets-30.0%-31.4%-77.9%-67.9%-88.9%
Return on equity-42.5%-169.1%-198.0%-126.8%-137.7%
Return on invested capital-32.7%-31.7%-85.7%-64.5%-71.7%
Return on capital employed-32.8%-32.1%-86.4%-65.7%-73.0%
Earnings yield-46.8%-25.4%-67.8%-148.8%-150.4%
Free cash flow yield-52.4%-93.7%-64.8%-122.4%-121.3%
Capex / Op. cash flow-3.5%-5.6%-0.1%-0.1%-0.9%
Capex / Depreciation234.9%920.4%14.3%20.1%32.5%
Capex / Sales8.5%286.5%0.0%0.0%0.0%
SG&A / Sales123.9%2405.9%0.0%0.0%0.0%
R&D / Sales205.7%3192.9%0.0%0.0%0.0%
Stock comp / Sales12.2%320.8%0.0%0.0%0.0%
Intangibles / Total assets9.2%18.7%11.8%11.2%14.8%
Days sales outstanding6d244d0d0d0d
Days payables outstanding332d3948d0d0d826d
Operating cycle267d1534d0d0d0d
Cash conversion cycle-65d-2414d0d0d-826d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▲+14.7%EV / Sales ▼-98.7%EV / EBITDA ▲+93.1%EV / Op. cash flow ▲+0.954Earnings yield ▼-0.214
Profitability
Return on equity ▲+1.266Return on assets ▼-0.017Return on invested capital ▼-0.010Return on capital employed ▼-0.008Operating ROA ▼-0.150Income quality ▼-2.414Tax burden ▼-0.008
Efficiency
Days sales outstanding ▼-238.138Days payables outstanding ▼-3615.863Operating cycle ▼-1266.951Cash conversion cycle ▲+2348.911Capex / Sales ▼-2.780R&D / Sales ▼-29.872
Balance-sheet strength
Current ratio ▲+6.744Net debt / EBITDA ▲+2.837Working capital ▲+156522000.000Invested capital ▲+152522000.000Intangibles / Total assets ▼-0.095

Change over 5 years

Valuation
Market cap ▲+186.9%EV / Sales n/aEV / EBITDA ▼-108.9%EV / Op. cash flow ▼-0.104Earnings yield ▲+1.036
Profitability
Return on equity ▲+0.952Return on assets ▲+0.484Return on invested capital ▲+0.390Return on capital employed ▲+0.402Operating ROA ▲+0.230Income quality ▲+0.282Tax burden +0.000
Efficiency
Days sales outstanding n/aDays payables outstanding ▼-493.992Operating cycle n/aCash conversion cycle ▲+761.229Capex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▲+3.889Net debt / EBITDA ▲+1.520Working capital ▲+161965000.000Invested capital ▲+162582000.000Intangibles / Total assets ▼-0.056

Employee count

Peer market caps

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