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RVMD

Bearish signalScored 2026-10-11 Drivers: trend, fundamentals. Insiders: neutral. Moteurs : tendance, fondamentaux. Initiés : neutre.

Research, not advice.

À propos

Revolution Medicines, Inc.

Nom
Revolution Medicines, Inc.
Secteur
Healthcare
Industrie
Biotechnology
Bourse
NASDAQ
Capitalisation
$40.1B
Employés
883
PDG
Mark A. Goldsmith
Site web
https://www.revmed.com
Marché
BDTXELVNERASGLUEIDYANRIX

Revolution Medicines, Inc. is a precision oncology firm operating in the clinical development stage, dedicated to creating innovative treatments that target novel pathways crucial for RAS-driven cancers. Its pipeline includes several promising drug candidates: RMC-4630, an SHP2 inhibitor, is currently undergoing Phase 1/2 clinical trials for various solid tumors, such as gynecological and colorectal cancers. The company's portfolio also features RMC-5845, a selective inhibitor designed to target SOS1, a protein responsible for activating RAS within cells, and RMC-5552, a highly selective inhibitor for hyperactive mTORC1 signaling found in cancerous cells. Further expanding its therapeutic arsenal, Revolution Medicines is advancing RMC-6291, which selectively inhibits mutated forms of KRASG12C(ON) and NRASG12C(ON). Another promising compound, RMC-6236, specifically targets and inhibits a range of active RAS(ON) variants. Its research efforts also encompass other active RAS inhibitors aimed at KRASG13C(ON) and KRASG12D(ON) mutations. Revolution Medicines has established a collaborative partnership with Sanofi to research and develop SHP2 inhibitors, a collaboration that includes the development of RMC-4630. Established in 2014, Revolution Medicines, Inc. operates from its corporate headquarters situated in Redwood City, California.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

VENTE TOTALE: 104 131 titres (~21 252 374,75 $ US)

Insiders
ANDERSON ELIZABETH MGOLDSMITH MARK A
Total bought
—

Avg buy (VWAP, 90d window) —

Total sold
$10,220,691

Avg sell (VWAP, 90d window) $201.66 vs last close $177.96 (-11.8%)

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

$10,220,691 of that total is under a Rule 10b5-1 plan. It is shown here and left out of the score.

Last activity
2026-09-22
Liquidity
Liquid $395,661,547/day · 20d vol
Last synced
2026-10-18 09:40:49 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-09-29 Sandler Alan B. Sell · S · 10b5-1 301 $204.72 $61,621 Form 4
2026-09-25 Cislini Jeff Sell · S · 10b5-1 765 $207.32 $158,600 Form 4
2026-09-25 Mancini Anthony Sell · S · 10b5-1 3,121 $200.54 $625,885 Form 4
2026-09-24 Mancini Anthony Sell · S · 10b5-1 587 $200.00 $117,400 Form 4
2026-09-22 ANDERSON ELIZABETH M Sell · S · 10b5-1 100 $195.15 $19,515 Form 4
2026-09-18 Mancini Anthony Sell · S · 10b5-1 1,764 $196.94 $347,402 Form 4
2026-09-16 Anders Jack Sell · S · 10b5-1 3,992 $199.30 $795,618 Form 4
2026-09-16 Cislini Jeff Sell · S · 10b5-1 3,314 $199.30 $660,491 Form 4
2026-09-16 GOLDSMITH MARK A Sell · S · 10b5-1 13,775 $199.30 $2,745,402 Form 4
2026-09-16 Horn Margaret A Sell · S · 10b5-1 4,891 $199.30 $974,792 Form 4
2026-09-16 Kelsey Stephen Michael Sell · S · 10b5-1 5,484 $199.30 $1,092,979 Form 4
2026-09-16 Mancini Anthony Sell · S · 10b5-1 1,747 $199.30 $348,183 Form 4
2026-09-16 Sandler Alan B. Sell · S · 10b5-1 336 $199.30 $66,966 Form 4
2026-09-11 Kelsey Stephen Michael Sell · S · 10b5-1 3,270 $205.81 $672,991 Form 4
2026-09-10 Mancini Anthony Sell · S · 10b5-1 300 $207.17 $62,152 Form 4
2026-08-21 Cislini Jeff Sell · S · 10b5-1 3,314 $212.06 $702,761 Form 4
2026-08-21 GOLDSMITH MARK A Sell · S · 10b5-1 3,621 $212.08 $767,933 Form 4

Sales marked 10b5-1 are scheduled in advance and don't count toward the Quorum score. Les ventes marquées 10b5-1 sont planifiées à l'avance et ne pèsent pas dans le score Quorum.

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Signal

Bearish signalScored 2026-10-11 Drivers: trend, fundamentals. Insiders: neutral. Moteurs : tendance, fondamentaux. Initiés : neutre.

RVMD is a pre-revenue biotech with zero revenue, persistent cash burn, and no near-term path to profitability, making its weak fundamental trajectory (score: 25) a critical concern despite adequate liquidity (score: 85).

The first sentence of the analysis written for RVMD on 2026-10-11 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Bearish signal Drivers: trend, fundamentals. Insiders: neutral. Moteurs : tendance, fondamentaux. Initiés : neutre.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Unavailable or mixed. – Insider: neutral. All sales (≈ $9.3M) were pre-planned Rule 10b5-1 trades, excluded from the score. No open-market buys or discretionary sales. – Initiés : neutre. Toutes les ventes (≈ $9.3M) sont sous plan 10b5-1 préétabli, exclues du score. Aucun achat ni vente discrétionnaire.
  • Congress Unavailable or mixed. No purchase disclosures in the stored window
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Timing Pulls against a bullish reading. Close is more than 0.5 ATR under stored support
  • Financial indicators Supports a bullish reading. Current ratio 7.14 · operating margin 0.0%

Suggested stop 136.77, nearest stored support minus 0.5 ATR(23.1% under the last close). Reward/risk to the next stored resistance is 1.13. Wait — that reward/risk is under 2. Research, not advice. Not an order.

Market snapshot

Financial ratios

MetricTrend2025-12-312024-12-312023-12-312022-12-312021-12-31
Gross Profit Margin0.0%0.0%100.0%100.0%100.0%
Ebit Margin0.0%0.0%-3796.1%-704.1%-636.5%
Ebitda Margin0.0%0.0%-3715.7%-676.8%-611.6%
Operating Profit Margin0.0%0.0%-4207.1%-730.0%-639.7%
Pretax Profit Margin0.0%0.0%-3798.7%-704.1%-636.6%
Continuous Operations Profit Margin0.0%0.0%-3768.3%-703.0%-636.6%
Net Profit Margin0.0%0.0%-3768.3%-703.0%-636.6%
Bottom Line Profit Margin0.0%0.0%-3768.3%-703.0%-636.6%
Current Ratio7.14514.20013.06410.6519.773
Quick Ratio7.14514.20013.06410.6519.773
Solvency Ratio-1.541-2.007-1.813-1.886-1.327
Cash Ratio1.3213.3134.8392.6041.798
Price To Earnings Ratio-13.387-12.218-7.430-7.734-10.190
Price To Earnings Growth Ratio-0.2021.684-0.293-0.313-0.194
Forward Price To Earnings Growth Ratio-0.2021.684-0.293-0.313-0.194
Price To Earnings Diluted Ratio-13.387-12.218-7.430-7.734-10.190
Price To Earnings Diluted Growth Ratio-0.2021.684-0.293-0.313-0.194
Price To Book Ratio9.2833.2391.7772.8033.041
Price To Sales Ratio0.0000.000280.23654.28362.352
Price To Free Cash Flow Ratio-16.574-12.923-9.057-8.165-11.922
Price To Operating Cash Flow Ratio-16.869-13.162-9.257-8.558-12.451
Debt To Assets Ratio0.0670.0530.0430.0790.090
Debt To Equity Ratio0.0970.0600.0480.0940.111
Debt To Capital Ratio0.0890.0570.0460.0860.100
Long Term Debt To Capital Ratio0.0800.0000.0000.0000.000
Financial Leverage Ratio1.4431.1291.1291.1851.225
Working Capital Turnover Ratio0.0000.0000.0100.0630.063
Operating Cash Flow Ratio-3.091-3.401-2.437-3.620-2.439
Operating Cash Flow Sales Ratio0.0000.000-30.274-6.343-5.008
Free Cash Flow Operating Cash Flow Ratio1.0181.0181.0221.0481.044
Debt Service Coverage Ratio-45.0050.000-1,408.4320.000-14,978.917
Interest Coverage Ratio-48.7960.000-1,607.8710.000-15,667.333
Short Term Operating Cash Flow Coverage Ratio0.0000.0000.0000.0000.000
Operating Cash Flow Coverage Ratio-5.657-4.104-3.986-3.495-2.209
Capital Expenditure Coverage Ratio-56.144-54.078-45.358-20.747-22.546
Dividend Paid And Capex Coverage Ratio-56.144-54.078-45.358-20.747-22.546
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple-13.680-11.765-6.128-7.614-9.962

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 0.0% 0.0% ▼-60.0%
Ebit Margin 0.0% 0.0% ▲1027.4%
Ebitda Margin 0.0% 0.0% ▲1000.8%
Operating Profit Margin 0.0% 0.0% ▲1115.4%
Pretax Profit Margin 0.0% 0.0% ▲1027.9%
Continuous Operations Profit Margin 0.0% 0.0% ▲1021.6%
Net Profit Margin 0.0% 0.0% ▲1021.6%
Bottom Line Profit Margin 0.0% 0.0% ▲1021.6%
Current Ratio 7.145 ▼-7.056 ▼-3.822
Quick Ratio 7.145 ▼-7.056 ▼-3.822
Solvency Ratio -1.541 ▲0.466 ▲0.174
Cash Ratio 1.321 ▼-1.992 ▼-1.454
Price To Earnings Ratio -13.387 ▼-1.169 ▼-3.195
Price To Earnings Growth Ratio -0.202 ▼-1.887 ▼-0.339
Forward Price To Earnings Growth Ratio -0.202 ▼-1.887 ▼-0.339
Price To Earnings Diluted Ratio -13.387 ▼-1.169 ▼-3.195
Price To Earnings Diluted Growth Ratio -0.202 ▼-1.887 ▼-0.339
Price To Book Ratio 9.283 ▲6.044 ▲5.255
Price To Sales Ratio 0.000 0.000 ▼-79.374
Price To Free Cash Flow Ratio -16.574 ▼-3.651 ▼-4.846
Price To Operating Cash Flow Ratio -16.869 ▼-3.707 ▼-4.809
Debt To Assets Ratio 0.067 ▲0.014 ▲0.001
Debt To Equity Ratio 0.097 ▲0.037 ▲0.015
Debt To Capital Ratio 0.089 ▲0.032 ▲0.013
Long Term Debt To Capital Ratio 0.080 ▲0.080 ▲0.064
Financial Leverage Ratio 1.443 ▲0.314 ▲0.221
Working Capital Turnover Ratio 0.000 0.000 ▼-0.027
Operating Cash Flow Ratio -3.091 ▲0.310 ▼-0.093
Operating Cash Flow Sales Ratio 0.000 0.000 ▲8.325
Free Cash Flow Operating Cash Flow Ratio 1.018 ▼-0.001 ▼-0.012
Debt Service Coverage Ratio -45.005 ▼-45.005 ▲3241.466
Interest Coverage Ratio -48.796 ▼-48.796 ▲3416.004
Short Term Operating Cash Flow Coverage Ratio 0.000 0.000 0.000
Operating Cash Flow Coverage Ratio -5.657 ▼-1.553 ▼-1.767
Capital Expenditure Coverage Ratio -56.144 ▼-2.066 ▼-16.369
Dividend Paid And Capex Coverage Ratio -56.144 ▼-2.066 ▼-16.369
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple -13.681 ▼-1.916 ▼-3.851

Key metrics

MetricTrend20252024202320222021
Market cap$15.14B$7.34B$3.25B$1.92B$1.83B
Enterprise value$14.92B$6.93B$2.64B$1.82B$1.79B
EV / Sales0.00x0.00x227.72x51.53x60.93x
EV / Op. cash flow-16.62x-12.43x-7.52x-8.12x-12.17x
EV / Free cash flow-16.33x-12.21x-7.36x-7.75x-11.65x
EV / EBITDA-13.68x-11.77x-6.13x-7.61x-9.96x
Net debt / EBITDA0.21x0.69x1.41x0.41x0.23x
Current ratio7.14x14.20x13.06x10.65x9.77x
Income quality0.79x0.93x0.80x0.90x0.79x
Graham net-net$7$12$14$6$6
Tax burden100.0%99.9%99.2%99.8%100.0%
Interest burden102.2%100.0%100.1%100.0%100.0%
Working capital$1.78B$2.16B$1.74B$598.2M$529.4M
Invested capital$2.02B$2.38B$1.91B$745.4M$675.1M
Return on assets-48.0%-23.5%-21.2%-30.6%-25.4%
Operating ROA-48.1%-29.8%-33.9%-33.3%-28.8%
Return on tangible assets-49.5%-24.1%-21.9%-33.7%-28.2%
Return on equity-69.3%-26.5%-23.9%-36.3%-31.0%
Return on invested capital-56.8%-28.6%-25.1%-34.1%-27.5%
Return on capital employed-57.3%-28.8%-25.4%-34.4%-27.7%
Earnings yield-7.5%-8.2%-13.4%-12.9%-10.2%
Free cash flow yield-6.0%-7.7%-11.0%-12.2%-8.4%
Capex / Op. cash flow-1.8%-1.8%-2.2%-4.8%-4.4%
Capex / Depreciation-59.3%87.2%83.0%112.0%89.0%
Capex / Sales0.0%0.0%66.7%30.6%22.2%
SG&A / Sales0.0%0.0%653.0%114.7%103.6%
R&D / Sales0.0%0.0%3654.1%715.3%636.1%
Stock comp / Sales0.0%0.0%533.4%88.2%70.5%
Intangibles / Total assets3.0%2.8%3.5%9.0%10.1%
Days sales outstanding0d0d40d48d74d
Days payables outstanding1424d0d0d0d0d
Operating cycle0d0d40d48d74d
Cash conversion cycle-1424d0d40d48d74d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▲+106.4%EV / Sales n/aEV / EBITDA ▼-16.3%EV / Op. cash flow ▼-4.187Earnings yield ▲+0.007
Profitability
Return on equity ▼-0.429Return on assets ▼-0.246Return on invested capital ▼-0.282Return on capital employed ▼-0.285Operating ROA ▼-0.183Income quality ▼-0.135Tax burden ▲+0.001
Efficiency
Days sales outstanding n/aDays payables outstanding n/aOperating cycle n/aCash conversion cycle n/aCapex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▼-7.055Net debt / EBITDA ▼-0.485Working capital ▼-379105000.000Invested capital ▼-356520000.000Intangibles / Total assets ▲+0.002

Change over 5 years

Valuation
Market cap ▲+726.4%EV / Sales ▼-100.0%EV / EBITDA ▼-37.3%EV / Op. cash flow ▼-4.452Earnings yield ▲+0.027
Profitability
Return on equity ▼-0.383Return on assets ▼-0.227Return on invested capital ▼-0.293Return on capital employed ▼-0.295Operating ROA ▼-0.193Income quality ▲+0.007Tax burden 0.000
Efficiency
Days sales outstanding ▼-73.633Days payables outstanding n/aOperating cycle ▼-73.633Cash conversion cycle ▼-1498.011Capex / Sales ▼-0.222R&D / Sales ▼-6.361
Balance-sheet strength
Current ratio ▼-2.628Net debt / EBITDA ▼-0.027Working capital ▲+1255190000.000Invested capital ▲+1345156000.000Intangibles / Total assets ▼-0.071

Employee count

Peer market caps

Recent news