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OMER

Bearish signalScored 2026-09-27 Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

Research, not advice.

À propos

Omeros Corporation

Nom
Omeros Corporation
Secteur
Healthcare
Industrie
Biotechnology
Bourse
NASDAQ
Capitalisation
$1.2B
Employés
175
PDG
Gregory A. Demopulos
Site web
https://www.omeros.com
Marché
ANABBHVNCGEMCGENCRVSMGNX

Omeros Corporation is a biopharmaceutical firm with commercialized products, actively engaged in the discovery, development, and market introduction of both small-molecule and protein-based therapies, including treatments for rare diseases. The company's therapeutic endeavors primarily focus on inflammatory conditions, illnesses mediated by the complement system, cancers linked to immune system dysregulation, and disorders characterized by addiction or compulsion. Its robust clinical pipeline features several promising candidates. Narsoplimab (also known as OMS721 or MASP-2), a leading asset, has successfully concluded pivotal trials for hematopoietic stem-cell transplant-associated thrombotic microangiopathy (HSCT-TMA). This drug is also currently undergoing Phase III clinical evaluation for immunoglobulin A nephropathy (IgAN) and atypical hemolytic uremic syndrome (aHUS), in addition to a Phase II trial investigating its potential for treating COVID-19. Further expanding its clinical portfolio, Omeros is developing PPAR? (OMS405) in Phase II for opioid and nicotine dependence. PDE7 (OMS527) is progressing through Phase I studies for addiction, compulsive disorders, and movement disorders. Additionally, MASP-3 (OMS906) is currently in Phase I trials for paroxysmal nocturnal hemoglobinuria (PNH) and other conditions involving the alternative complement pathway. Beyond its clinical efforts, the company maintains a dynamic preclinical program. This includes small-molecule inhibitors targeting MASP-2, which are being explored for applications in aHUS, IgAN, HSCT-TMA, and age-related macular degeneration. Also in development is a next-generation, longer-acting antibody that targets MASP-2, alongside MASP-3 small-molecule inhibitors designed to address PNH and other alternative pathway disorders. Omeros's preclinical research further encompasses GPR174 inhibitors, as well as Chimeric Antigen Receptor (CAR) T-Cell and Adoptive T-Cell Therapies for various oncological indications. The company is also investigating G protein-coupled receptor targets for a broad spectrum of diseases, including immunological, immuno-oncological, metabolic, central nervous system (CNS), cardiovascular, musculoskeletal, and other conditions. Established in 1994, Omeros Corporation is headquartered in Seattle, Washington.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

VENTE TOTALE: 30 000 titres (~558 167,00 $ US)

Insiders
HANISH ARNOLD CCable Thomas J.
Total bought
—

Avg buy (VWAP, 90d window) —

Total sold
$1,895,208

Avg sell (VWAP, 90d window) $18.78 vs last close $18.61 (-0.9%)

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

$501,055 of that total is under a Rule 10b5-1 plan. It is shown here and left out of the score.

Last activity
2026-08-27
Liquidity
Liquid $27,452,767/day · 20d vol
Last synced
2026-10-02 21:10:44 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-09-23 Borges David J. Sell · S · 10b5-1 10,000 $20.95 $209,500 Form 4
2026-08-31 Cancelmo Peter B Sell · S 25,000 $18.54 $463,540 Form 4
2026-08-28 Cancelmo Peter B Sell · S 25,000 $18.65 $466,128 Form 4
2026-08-27 HANISH ARNOLD C Sell · S 5,000 $19.02 $95,081 Form 4
2026-08-26 HANISH ARNOLD C Sell · S 5,000 $18.53 $92,632 Form 4
2026-08-24 Borges David J. Sell · S · 10b5-1 906 $19.10 $17,305 Form 4
2026-08-21 Borges David J. Sell · S · 10b5-1 10,000 $18.95 $189,500 Form 4
2026-08-20 Cable Thomas J. Sell · S 15,000 $18.45 $276,772 Form 4
2026-08-13 Borges David J. Sell · S · 10b5-1 5,000 $16.95 $84,750 Form 4

Sales marked 10b5-1 are scheduled in advance and don't count toward the Quorum score. Les ventes marquées 10b5-1 sont planifiées à l'avance et ne pèsent pas dans le score Quorum.

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Signal

Bearish signalScored 2026-09-27 Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

OMER presents a compelling event-driven catalyst — a significant earnings beat, strong YARTEMLEA launch revenues, and new BlackRock institutional backing — but these positives are severely undermined by catastrophic…

The first sentence of the analysis written for OMER on 2026-09-27 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Bearish signal Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Pulls against a bullish reading. Selling cluster — sale value, no purchase value
  • Congress Unavailable or mixed. No purchase disclosures in the stored window
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Timing Supports a bullish reading. Interesting trend — weekly bias up
  • Financial indicators Supports a bullish reading. Current ratio 2.76 · operating margin 0.0%

Suggested stop 16.04, nearest stored support minus 0.5 ATR(13.8% under the last close). Reward/risk to the next stored resistance is 0.44. Wait — that reward/risk is under 2. Research, not advice. Not an order.

Market snapshot

Financial ratios

MetricTrend2025-12-312024-12-312023-12-312022-12-312021-12-31
Gross Profit Margin0.0%0.0%0.0%0.0%0.0%
Ebit Margin0.0%0.0%0.0%0.0%0.0%
Ebitda Margin0.0%0.0%0.0%0.0%0.0%
Operating Profit Margin0.0%0.0%0.0%0.0%0.0%
Pretax Profit Margin0.0%0.0%0.0%0.0%0.0%
Continuous Operations Profit Margin0.0%0.0%0.0%0.0%0.0%
Net Profit Margin0.0%0.0%0.0%0.0%0.0%
Bottom Line Profit Margin0.0%0.0%0.0%0.0%0.0%
Current Ratio2.7631.6864.0873.2504.788
Quick Ratio2.7631.6864.0873.2504.788
Solvency Ratio-0.005-0.339-0.2900.096-0.278
Cash Ratio0.1240.0430.1330.0811.947
Price To Earnings Ratio-325.996-3.659-1.7394.913-3.592
Price To Earnings Growth Ratio3.325-0.0840.003-0.0390.140
Forward Price To Earnings Growth Ratio3.325-0.0840.003-0.0390.140
Price To Earnings Diluted Ratio-325.996-3.659-1.7394.913-3.592
Price To Earnings Diluted Growth Ratio3.325-0.0840.003-0.0390.140
Price To Book Ratio-9.000-3.147-8.2121.65516.858
Price To Sales Ratio0.0000.0000.0000.0000.000
Price To Free Cash Flow Ratio-9.393-3.8582.761-1.637-3.644
Price To Operating Cash Flow Ratio-9.398-3.8622.745-1.639-3.654
Debt To Assets Ratio0.7340.7470.9560.5790.830
Debt To Equity Ratio-1.973-1.134-14.4733.99214.627
Debt To Capital Ratio2.0288.4811.0740.8000.936
Long Term Debt To Capital Ratio2.389-10.3951.0820.7210.929
Financial Leverage Ratio-2.686-1.517-15.1416.89717.631
Working Capital Turnover Ratio0.0000.0000.0000.0000.000
Operating Cash Flow Ratio-1.487-1.8711.402-0.634-2.119
Operating Cash Flow Sales Ratio0.0000.0000.0000.0000.000
Free Cash Flow Operating Cash Flow Ratio1.0011.0010.9941.0011.003
Debt Service Coverage Ratio-0.225-3.437-3.632-1.353-8.668
Interest Coverage Ratio0.000-6.859-5.334-7.197-8.827
Short Term Operating Cash Flow Coverage Ratio-6.804-7.0868.713-0.9160.000
Operating Cash Flow Coverage Ratio-0.485-0.7190.207-0.253-0.315
Capital Expenditure Coverage Ratio-1,786.062-901.836175.413-765.336-396.108
Dividend Paid And Capex Coverage Ratio-1,786.062-901.836175.413-765.336-396.108
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple-720.845-4.958-3.909-2.985-3.800

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 0.0% 0.0% 0.0%
Ebit Margin 0.0% 0.0% 0.0%
Ebitda Margin 0.0% 0.0% 0.0%
Operating Profit Margin 0.0% 0.0% 0.0%
Pretax Profit Margin 0.0% 0.0% 0.0%
Continuous Operations Profit Margin 0.0% 0.0% 0.0%
Net Profit Margin 0.0% 0.0% 0.0%
Bottom Line Profit Margin 0.0% 0.0% 0.0%
Current Ratio 2.763 ▲1.076 ▼-0.552
Quick Ratio 2.763 ▲1.076 ▼-0.552
Solvency Ratio -0.005 ▲0.334 ▲0.158
Cash Ratio 0.124 ▲0.081 ▼-0.342
Price To Earnings Ratio -325.996 ▼-322.337 ▼-259.981
Price To Earnings Growth Ratio 3.325 ▲3.409 ▲2.656
Forward Price To Earnings Growth Ratio 3.325 ▲3.409 ▲2.656
Price To Earnings Diluted Ratio -325.996 ▼-322.337 ▼-259.981
Price To Earnings Diluted Growth Ratio 3.325 ▲3.409 ▲2.656
Price To Book Ratio -9.000 ▼-5.853 ▼-8.631
Price To Sales Ratio 0.000 0.000 0.000
Price To Free Cash Flow Ratio -9.393 ▼-5.535 ▼-6.239
Price To Operating Cash Flow Ratio -9.399 ▼-5.536 ▼-6.237
Debt To Assets Ratio 0.734 ▼-0.013 ▼-0.035
Debt To Equity Ratio -1.973 ▼-0.839 ▼-2.180
Debt To Capital Ratio 2.028 ▼-6.452 ▼-0.636
Long Term Debt To Capital Ratio 2.389 ▲12.783 ▲3.443
Financial Leverage Ratio -2.686 ▼-1.169 ▼-3.723
Working Capital Turnover Ratio 0.000 0.000 0.000
Operating Cash Flow Ratio -1.487 ▲0.384 ▼-0.545
Operating Cash Flow Sales Ratio 0.000 0.000 0.000
Free Cash Flow Operating Cash Flow Ratio 1.001 ▼-0.001 ▲0.001
Debt Service Coverage Ratio -0.225 ▲3.212 ▲3.238
Interest Coverage Ratio 0.000 ▲6.859 ▲5.644
Short Term Operating Cash Flow Coverage Ratio -6.804 ▲0.282 ▼-5.585
Operating Cash Flow Coverage Ratio -0.485 ▲0.233 ▼-0.172
Capital Expenditure Coverage Ratio -1786.062 ▼-884.225 ▼-1051.276
Dividend Paid And Capex Coverage Ratio -1786.062 ▼-884.225 ▼-1051.276
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple -720.845 ▼-715.888 ▼-573.546

Key metrics

MetricTrend20252024202320222021
Market cap$1.09B$574.7M$205.2M$141.8M$400.9M
Enterprise value$1.32B$778.3M$559.6M$472.8M$647.9M
EV / Sales0.00x0.00x0.00x0.00x0.00x
EV / Op. cash flow-11.38x-5.23x7.49x-5.47x-5.91x
EV / Free cash flow-11.37x-5.22x7.53x-5.46x-5.89x
EV / EBITDA-720.85x-4.96x-3.91x-2.98x-3.80x
Net debt / EBITDA-125.26x-1.30x-2.48x-2.09x-1.45x
Current ratio2.76x1.69x4.09x3.25x4.79x
Income quality34.66x0.95x-0.63x0.47x0.57x
Graham number———$5—
Graham net-net-$4-$6-$4-$2-$3
Tax burden119.8%85.9%67.4%-26.0%58.2%
Interest burden100.0%115.6%121.4%114.2%111.4%
Working capital$137.6M$54.6M$164.6M$306.9M$196.2M
Invested capital$150.1M$72.2M$185.2M$330.1M$226.2M
Return on assets-1.0%-56.6%-31.1%8.0%-26.6%
Operating ROA-40.7%-51.7%-34.0%-32.3%-57.8%
Return on tangible assets-1.0%-56.6%-31.1%8.0%-26.6%
Return on equity2.8%85.9%471.6%55.3%-468.5%
Return on invested capital-45.3%-75.4%-48.6%-29.5%-46.6%
Return on capital employed-49.6%-85.7%-50.6%-35.9%-47.2%
Earnings yield-0.3%-27.3%-57.4%33.4%-27.8%
Free cash flow yield-10.6%-25.9%36.2%-61.1%-27.4%
Capex / Op. cash flow-0.1%-0.1%0.6%-0.1%-0.3%
Capex / Depreciation6.7%17.4%46.3%11.9%20.0%
Capex / Sales0.0%0.0%0.0%0.0%0.0%
SG&A / Sales0.0%0.0%0.0%0.0%0.0%
R&D / Sales0.0%0.0%0.0%0.0%0.0%
Stock comp / Sales0.0%0.0%0.0%0.0%0.0%
Intangibles / Total assets0.0%0.0%0.0%0.0%0.0%
Days sales outstanding0d0d0d0d0d
Days payables outstanding0d0d0d0d3529d
Operating cycle0d0d0d0d0d
Cash conversion cycle0d0d0d0d-3529d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▲+89.8%EV / Sales n/aEV / EBITDA ▼-14440.5%EV / Op. cash flow ▼-6.144Earnings yield ▲+0.270
Profitability
Return on equity ▼-0.831Return on assets ▲+0.556Return on invested capital ▲+0.301Return on capital employed ▲+0.361Operating ROA ▲+0.109Income quality ▲+33.706Tax burden ▲+0.339
Efficiency
Days sales outstanding n/aDays payables outstanding n/aOperating cycle n/aCash conversion cycle n/aCapex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▲+1.076Net debt / EBITDA ▼-123.967Working capital ▲+83011000.000Invested capital ▲+77848000.000Intangibles / Total assets n/a

Change over 5 years

Valuation
Market cap ▲+172.2%EV / Sales n/aEV / EBITDA ▼-18868.5%EV / Op. cash flow ▼-5.470Earnings yield ▲+0.275
Profitability
Return on equity ▲+4.713Return on assets ▲+0.255Return on invested capital ▲+0.013Return on capital employed ▼-0.024Operating ROA ▲+0.171Income quality ▲+34.082Tax burden ▲+0.616
Efficiency
Days sales outstanding n/aDays payables outstanding ▼-3528.860Operating cycle n/aCash conversion cycle ▲+3528.860Capex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▼-2.025Net debt / EBITDA ▼-123.815Working capital ▼-58562000.000Invested capital ▼-76093000.000Intangibles / Total assets n/a

Employee count

Peer market caps

Recent news