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HEPA

Neutral signalScored 2026-09-06 Drivers: fundamentals. Moteurs : fondamentaux.

Research, not advice.

À propos

Hepion Pharmaceuticals, Inc.

Nom
Hepion Pharmaceuticals, Inc.
Secteur
Healthcare
Industrie
Biotechnology
Bourse
OTC
Capitalisation
$1.6M
Employés
2
PDG
Sireesh Appajosyula
Site web
https://www.hepionpharma.com
Marché
CDTCOCHENVBLIXTNIVFPTPI

Hepion Pharmaceuticals, Inc., a U.S.-based biopharmaceutical entity, is dedicated to developing therapeutic interventions for chronic hepatic ailments. Central to their efforts is Rencofilstat, a cyclophilin inhibitor that has successfully concluded Phase 2a clinical trials. This compound operates by disrupting multiple pathological pathways implicated in the worsening of liver disease. It is currently progressing through clinical development for non-alcoholic steatohepatitis (NASH) and is additionally being explored in nonclinical research for its potential to reduce liver fibrosis and lessen hepatocellular carcinoma tumor loads in experimental models of NASH. Moreover, Rencofilstat has exhibited antiviral properties against hepatitis B, C, and D viruses through diverse mechanisms. The company, established in 2013 and situated in Edison, New Jersey, rebranded as Hepion Pharmaceuticals, Inc. in July 2019, having previously operated as ContraVir Pharmaceuticals, Inc.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

ACHAT TOTAL: 6500000 titres (~390000 USD)

Insiders
Appajosyula SireeshPurcell Michael J.Stetz Gary S.Stetz Gary S. II
Total bought
$390,000

Avg buy (VWAP, 90d window) $0.06 vs last close —

Total sold
—

Avg sell (VWAP, 90d window) —

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

Last activity
2026-08-03
Last synced
2026-08-14 10:30:55 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-09-29 Fisher Danina Buy · P 200,000 $0.06 $12,000 Form 4
2026-08-03 Appajosyula Sireesh Buy · P 2,000,000 $0.06 $120,000 Form 4
2026-08-03 Purcell Michael J. Buy · P 2,000,000 $0.06 $120,000 Form 4
2026-08-03 Stetz Gary S. Buy · P 2,000,000 $0.06 $120,000 Form 4
2026-08-03 Stetz Gary S. II Buy · P 500,000 $0.06 $30,000 Form 4

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Signal

Neutral signalScored 2026-09-06 Drivers: fundamentals. Moteurs : fondamentaux.

While the insider cluster buy on HEPA is a notable signal — with 6.5M shares accumulated and zero offsetting sales — the underlying fundamentals are critically impaired: zero revenue, persistent negative cash flows, and…

The first sentence of the analysis written for HEPA on 2026-09-06 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Neutral signal Drivers: fundamentals. Moteurs : fondamentaux.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Supports a bullish reading. Open-market purchases outweigh sales
  • Congress Unavailable or mixed. No purchase disclosures in the stored window
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Timing Unavailable or mixed. No stored price series
  • Financial indicators Supports a bullish reading. Current ratio 10.25 · operating margin 0.0%

Market snapshot

Financial ratios

MetricTrend2025-12-312024-12-312023-12-312022-12-312021-12-31
Gross Profit Margin0.0%0.0%0.0%0.0%0.0%
Ebit Margin0.0%0.0%0.0%0.0%0.0%
Ebitda Margin0.0%0.0%0.0%0.0%0.0%
Operating Profit Margin0.0%0.0%0.0%0.0%0.0%
Pretax Profit Margin0.0%0.0%0.0%0.0%0.0%
Continuous Operations Profit Margin0.0%0.0%0.0%0.0%0.0%
Net Profit Margin0.0%0.0%0.0%0.0%0.0%
Bottom Line Profit Margin0.0%0.0%0.0%0.0%0.0%
Current Ratio10.2540.5133.3067.16411.875
Quick Ratio10.2540.5133.3067.16411.875
Solvency Ratio-20.495-3.785-4.518-4.055-3.091
Cash Ratio6.1060.1292.7956.49111.131
Price To Earnings Ratio-0.068-0.219-0.263-0.505-2.449
Price To Earnings Growth Ratio0.0010.003-0.073-0.0180.031
Forward Price To Earnings Growth Ratio0.0010.003-0.073-0.0180.031
Price To Earnings Diluted Ratio-0.068-0.219-0.263-0.505-2.449
Price To Earnings Diluted Growth Ratio0.0010.003-0.073-0.0180.031
Price To Book Ratio0.212-1.5511.7670.4590.862
Price To Sales Ratio0.0000.0000.0000.0000.000
Price To Free Cash Flow Ratio-0.173-0.159-0.315-0.654-2.556
Price To Operating Cash Flow Ratio-0.173-0.159-0.315-0.655-2.566
Debt To Assets Ratio0.0181.7970.0120.0010.003
Debt To Equity Ratio0.020-1.5560.0290.0010.003
Debt To Capital Ratio0.0202.7970.0280.0010.003
Long Term Debt To Capital Ratio0.0000.0000.0000.0000.000
Financial Leverage Ratio1.151-0.8662.4851.2081.114
Working Capital Turnover Ratio0.0000.0000.0000.0000.000
Operating Cash Flow Ratio-10.928-5.794-7.729-4.433-3.805
Operating Cash Flow Sales Ratio0.0000.0000.0000.0000.000
Free Cash Flow Operating Cash Flow Ratio1.0001.0001.0001.0001.004
Debt Service Coverage Ratio-47.535-2.873-5,161.061-4,143.292-3,682.948
Interest Coverage Ratio-170.601-15.511-5,118.643-4,475.475-3,431.912
Short Term Operating Cash Flow Coverage Ratio-60.510-6.2810.0000.0000.000
Operating Cash Flow Coverage Ratio-60.510-6.281-195.622-652.090-98.502
Capital Expenditure Coverage Ratio0.0000.000-2,858.562-2,140.130-239.442
Dividend Paid And Capex Coverage Ratio0.0000.000-2,858.562-2,140.130-239.442
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple0.324-0.3620.0350.6280.334

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 0.0% 0.0% 0.0%
Ebit Margin 0.0% 0.0% 0.0%
Ebitda Margin 0.0% 0.0% 0.0%
Operating Profit Margin 0.0% 0.0% 0.0%
Pretax Profit Margin 0.0% 0.0% 0.0%
Continuous Operations Profit Margin 0.0% 0.0% 0.0%
Net Profit Margin 0.0% 0.0% 0.0%
Bottom Line Profit Margin 0.0% 0.0% 0.0%
Current Ratio 10.254 ▲9.741 ▲3.632
Quick Ratio 10.254 ▲9.741 ▲3.632
Solvency Ratio -20.494 ▼-16.709 ▼-13.306
Cash Ratio 6.106 ▲5.977 ▲0.775
Price To Earnings Ratio -0.068 ▲0.151 ▲0.633
Price To Earnings Growth Ratio 0.001 ▼-0.002 ▲0.012
Forward Price To Earnings Growth Ratio 0.001 ▼-0.002 ▲0.012
Price To Earnings Diluted Ratio -0.068 ▲0.151 ▲0.633
Price To Earnings Diluted Growth Ratio 0.001 ▼-0.002 ▲0.012
Price To Book Ratio 0.212 ▲1.762 ▼-0.138
Price To Sales Ratio 0.000 0.000 0.000
Price To Free Cash Flow Ratio -0.173 ▼-0.014 ▲0.599
Price To Operating Cash Flow Ratio -0.173 ▼-0.014 ▲0.601
Debt To Assets Ratio 0.018 ▼-1.780 ▼-0.348
Debt To Equity Ratio 0.020 ▲1.577 ▲0.321
Debt To Capital Ratio 0.020 ▼-2.778 ▼-0.550
Long Term Debt To Capital Ratio 0.000 0.000 0.000
Financial Leverage Ratio 1.151 ▲2.017 ▲0.133
Working Capital Turnover Ratio 0.000 0.000 0.000
Operating Cash Flow Ratio -10.928 ▼-5.133 ▼-4.390
Operating Cash Flow Sales Ratio 0.000 0.000 0.000
Free Cash Flow Operating Cash Flow Ratio 1.000 0.000 ▼-0.001
Debt Service Coverage Ratio -47.535 ▼-44.663 ▲2560.007
Interest Coverage Ratio -170.601 ▼-155.090 ▲2471.827
Short Term Operating Cash Flow Coverage Ratio -60.510 ▼-54.228 ▼-47.151
Operating Cash Flow Coverage Ratio -60.510 ▼-54.228 ▲142.091
Capital Expenditure Coverage Ratio 0.000 0.000 ▲1047.627
Dividend Paid And Capex Coverage Ratio 0.000 0.000 ▲1047.627
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple 0.324 ▲0.686 ▲0.132

Key metrics

MetricTrend20252024202320222021
Market cap$565K$2.9M$12.9M$22.9M$80.1M
Enterprise value-$1.2M$5.4M-$1.7M-$28.2M-$10.9M
EV / Sales0.00x0.00x0.00x0.00x0.00x
EV / Op. cash flow0.37x-0.29x0.04x0.81x0.35x
EV / Free cash flow0.37x-0.29x0.04x0.81x0.35x
EV / EBITDA0.32x-0.36x0.04x0.63x0.33x
Net debt / EBITDA0.48x-0.17x0.30x1.14x2.79x
Current ratio10.25x0.51x3.31x7.16x11.88x
Income quality0.40x1.38x0.84x0.83x0.95x
Graham net-net$0-$25$50$535$1K
Tax burden100.0%81.6%99.2%93.6%100.0%
Interest burden220.1%108.4%100.0%100.0%100.0%
Working capital$2.8M-$1.5M$12.2M$48.6M$89.2M
Invested capital$2.8M-$1.5M$12.4M$55.1M$94.8M
Return on assets-269.6%-817.5%-270.4%-70.0%-31.6%
Operating ROA-177.8%-196.3%-123.7%-55.5%-40.0%
Return on tangible assets-269.6%-817.5%-270.4%-74.0%-33.2%
Return on equity-310.3%708.0%-672.0%-84.6%-35.2%
Return on invested capital-147.4%-1152.8%-371.9%-81.2%-31.8%
Return on capital employed-150.3%1264.4%-378.4%-86.9%-31.9%
Earnings yield-1466.2%-456.6%-380.3%-184.3%-40.8%
Free cash flow yield-579.5%-630.5%-317.9%-152.8%-39.1%
Capex / Op. cash flow0.0%0.0%-0.0%-0.0%-0.4%
Capex / Depreciation0.0%0.0%21.3%21.1%151.5%
Capex / Sales0.0%0.0%0.0%0.0%0.0%
SG&A / Sales0.0%0.0%0.0%0.0%0.0%
R&D / Sales0.0%0.0%0.0%0.0%0.0%
Stock comp / Sales0.0%0.0%0.0%0.0%0.0%
Intangibles / Total assets0.0%0.0%0.0%5.3%4.9%
Days sales outstanding0d0d0d0d0d
Days payables outstanding0d0d0d0d0d
Operating cycle0d0d0d0d0d
Cash conversion cycle0d0d0d0d0d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▼-80.5%EV / Sales n/aEV / EBITDA ▲+189.6%EV / Op. cash flow ▲+0.665Earnings yield ▼-10.096
Profitability
Return on equity ▼-10.183Return on assets ▲+5.479Return on invested capital ▲+10.054Return on capital employed ▼-14.146Operating ROA ▲+0.185Income quality ▼-0.986Tax burden ▲+0.184
Efficiency
Days sales outstanding n/aDays payables outstanding n/aOperating cycle n/aCash conversion cycle n/aCapex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▲+9.741Net debt / EBITDA ▲+0.643Working capital ▲+4300718.000Invested capital ▲+4300719.000Intangibles / Total assets n/a

Change over 5 years

Valuation
Market cap ▼-99.3%EV / Sales n/aEV / EBITDA ▼-2.9%EV / Op. cash flow ▲+0.021Earnings yield ▼-14.254
Profitability
Return on equity ▼-2.751Return on assets ▼-2.380Return on invested capital ▼-1.156Return on capital employed ▼-1.184Operating ROA ▼-1.378Income quality ▼-0.559Tax burden 0.000
Efficiency
Days sales outstanding n/aDays payables outstanding n/aOperating cycle n/aCash conversion cycle n/aCapex / Sales n/aR&D / Sales n/a
Balance-sheet strength
Current ratio ▼-1.621Net debt / EBITDA ▼-2.314Working capital ▼-86474803.000Invested capital ▼-91992188.000Intangibles / Total assets ▼-0.049

Employee count

Peer market caps

Recent news

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