HCWB
Neutral signalScored 2026-08-03 Drivers: fundamentals. Moteurs : fondamentaux.
Research, not advice.
À propos
HCW Biologics Inc.
- Nom
- HCW Biologics Inc.
- Secteur
- Healthcare
- Industrie
- Biotechnology
- Bourse
- NASDAQ
- Capitalisation
- $389K
- Employés
- 35
- PDG
- Hing C. Wong
- Site web
- https://www.hcwbiologics.com
- Marché
- ACXPADILAPREAPVOBCDABCLI
HCW Biologics Inc. operates as a preclinical-stage biopharmaceutical firm, primarily engaged in the discovery and advancement of novel immunotherapies. Its research and development efforts are focused on addressing chronic, low-grade inflammation and a spectrum of age-related diseases. The company's leading therapeutic candidates include HCW9218, an injectable immunotherapeutic designed for patients with a variety of cancers, such as pancreatic, ovarian, breast, prostate, and colorectal, as well as for pulmonary fibrosis. Another key product, HCW9302, targets autoimmune conditions like alopecia areata and various metabolic disorders. Beyond these, HCW Biologics is also developing HCW9201, a cell-based therapy currently in Phase II clinical trials for the treatment of relapsed/refractory acute myeloid leukemia. Additionally, HCW9206 is under development specifically for acute myeloid leukemia. Incorporated in 2018, the company's corporate headquarters are situated in Miramar, Florida.
Price (1 year)
Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.
ACHAT TOTAL: 23 210 titres (~59 997,85 $ US)
- Insiders
- Wong Hing C
- Total bought
-
$59,998
Avg buy (VWAP, 90d window) $2.58 vs last close —
- Total sold
-
—
Avg sell (VWAP, 90d window) —
Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.
- Last activity
- 2026-07-29
- Last synced
-
2026-10-19 22:07:50
Sign in to request a sync of this company's price history and timing levels.
Insider holdings as a share of total assets aren't available for this company.
Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.
Recent Form 4
Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.
| Date | Person | Side | Shares | Price | Value | Form 4 |
|---|---|---|---|---|---|---|
| 2026-07-29 | Flowers Lee | Buy · P | 7,736 | $2.58 | $19,998 | Form 4 |
| 2026-07-29 | Wong Hing C | Buy · P | 23,210 | $2.58 | $59,998 | Form 4 |
Congressional trades
STOCK Act disclosures (90-day window)
Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.
No STOCK Act disclosures for this company in this window.
Signal
Neutral signalScored 2026-08-03 Drivers: fundamentals. Moteurs : fondamentaux.
HCWB exhibits near-terminal financial distress with a current ratio of 0.11, persistent negative free cash flow, and an unsustainable burn rate that renders the business model structurally insolvent in the near term.
The first sentence of the analysis written for HCWB on 2026-08-03 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.
Factor checklist — research, not advice
A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.
- Insider Supports a bullish reading. Open-market purchases outweigh sales
- Congress Unavailable or mixed. No purchase disclosures in the stored window
- Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
- Timing Unavailable or mixed. No stored price series
- Financial indicators Pulls against a bullish reading. Current ratio 0.11 · operating margin -20758%
Market snapshot
Financial ratios
| Metric | Trend | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|---|
| Gross Profit Margin | 20.0% | 37.4% | 19.7% | 38.5% | 0.0% | |
| Ebit Margin | -12371.7% | -1124.6% | -869.6% | -219.8% | 0.0% | |
| Ebitda Margin | -10450.8% | -1078.4% | -829.6% | -209.1% | 0.0% | |
| Operating Profit Margin | -20757.6% | -1148.5% | -905.0% | -224.3% | 0.0% | |
| Pretax Profit Margin | -14677.1% | -1169.7% | -879.5% | -221.7% | 0.0% | |
| Continuous Operations Profit Margin | -14677.1% | -1169.7% | -879.5% | -221.7% | 0.0% | |
| Net Profit Margin | -14677.1% | -1169.7% | -879.5% | -221.7% | 0.0% | |
| Bottom Line Profit Margin | -41117.2% | -1169.7% | -879.5% | -221.7% | 0.0% | |
| Current Ratio | 0.108 | 0.192 | 0.732 | 11.524 | 17.436 | |
| Quick Ratio | 0.108 | 0.192 | 0.732 | 11.052 | 17.436 | |
| Solvency Ratio | -0.318 | -0.779 | -1.585 | -1.512 | -5.306 | |
| Cash Ratio | 0.093 | 0.158 | 0.411 | 7.552 | 5.053 | |
| Price To Earnings Ratio | -0.091 | -23.169 | -70.286 | -182.357 | -257.778 | |
| Price To Earnings Growth Ratio | -0.000 | -2.317 | -1.054 | -10.941 | -2.062 | |
| Forward Price To Earnings Growth Ratio | -0.000 | -2.317 | -1.054 | -10.941 | -2.062 | |
| Price To Earnings Diluted Ratio | -0.091 | -23.169 | -70.286 | -182.357 | -257.778 | |
| Price To Earnings Diluted Growth Ratio | -0.000 | -2.317 | -1.054 | -10.941 | -2.062 | |
| Price To Book Ratio | 0.736 | -102.223 | 131.315 | 73.303 | 64.839 | |
| Price To Sales Ratio | 37.520 | 269.623 | 622.047 | 408.151 | 0.000 | |
| Price To Free Cash Flow Ratio | -0.152 | -47.765 | -61.557 | -132.791 | -301.125 | |
| Price To Operating Cash Flow Ratio | -0.152 | -48.643 | -78.516 | -264.163 | -302.422 | |
| Debt To Assets Ratio | 0.278 | 0.453 | 0.221 | 0.137 | 0.000 | |
| Debt To Equity Ratio | 2.463 | -2.022 | 0.468 | 0.171 | 0.000 | |
| Debt To Capital Ratio | 0.711 | 1.978 | 0.319 | 0.146 | 0.000 | |
| Long Term Debt To Capital Ratio | 0.000 | 12.141 | 0.319 | 0.146 | 0.000 | |
| Financial Leverage Ratio | 8.869 | -4.466 | 2.118 | 1.251 | 1.045 | |
| Working Capital Turnover Ratio | -0.003 | -0.195 | 0.198 | 0.194 | 0.000 | |
| Operating Cash Flow Ratio | -0.636 | -0.480 | -2.574 | -3.513 | -4.728 | |
| Operating Cash Flow Sales Ratio | -246.932 | -5.543 | -7.923 | -1.545 | 0.000 | |
| Free Cash Flow Operating Cash Flow Ratio | 1.000 | 1.018 | 1.275 | 1.989 | 1.004 | |
| Debt Service Coverage Ratio | -0.703 | -3.704 | -83.295 | -110.976 | 0.000 | |
| Interest Coverage Ratio | -9.004 | -25.448 | -90.860 | -119.049 | 0.000 | |
| Short Term Operating Cash Flow Coverage Ratio | -1.967 | -2.253 | 0.000 | 0.000 | 0.000 | |
| Operating Cash Flow Coverage Ratio | -1.967 | -1.039 | -3.571 | -1.620 | 0.000 | |
| Capital Expenditure Coverage Ratio | -4,463,872.333 | -54.383 | -3.630 | -1.011 | -232.226 | |
| Dividend Paid And Capex Coverage Ratio | -4,463,872.333 | -54.383 | -3.630 | -1.011 | -232.226 | |
| Dividend Payout Ratio | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | |
| Enterprise Value Multiple | -1.216 | -25.327 | -75.095 | -194.058 | -268.496 |
Sparkline shows each ratio oldest → newest (left → right).
How the latest year compares
For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower
| Metric | Current | vs 1Y ago | vs 5Y avg |
|---|---|---|---|
| Gross Profit Margin | 20.0% | ▼-17.4% | ▼-3.1% |
| Ebit Margin | -12371.7% | ▼-11247.2% | ▼-9454.6% |
| Ebitda Margin | -10450.8% | ▼-9372.4% | ▼-7937.2% |
| Operating Profit Margin | -20757.7% | ▼-19609.2% | ▼-16150.6% |
| Pretax Profit Margin | -14677.1% | ▼-13507.4% | ▼-11287.5% |
| Continuous Operations Profit Margin | -14677.1% | ▼-13507.4% | ▼-11287.5% |
| Net Profit Margin | -14677.1% | ▼-13507.4% | ▼-11287.5% |
| Bottom Line Profit Margin | -41117.2% | ▼-39947.5% | ▼-32439.6% |
| Current Ratio | 0.108 | ▼-0.084 | ▼-5.890 |
| Quick Ratio | 0.108 | ▼-0.084 | ▼-5.796 |
| Solvency Ratio | -0.318 | ▲0.461 | ▲1.582 |
| Cash Ratio | 0.093 | ▼-0.065 | ▼-2.561 |
| Price To Earnings Ratio | -0.091 | ▲23.078 | ▲106.645 |
| Price To Earnings Growth Ratio | -0.000 | ▲2.317 | ▲3.275 |
| Forward Price To Earnings Growth Ratio | -0.000 | ▲2.317 | ▲3.275 |
| Price To Earnings Diluted Ratio | -0.091 | ▲23.078 | ▲106.645 |
| Price To Earnings Diluted Growth Ratio | -0.000 | ▲2.317 | ▲3.275 |
| Price To Book Ratio | 0.736 | ▲102.959 | ▼-32.858 |
| Price To Sales Ratio | 37.520 | ▼-232.104 | ▼-229.948 |
| Price To Free Cash Flow Ratio | -0.152 | ▲47.613 | ▲108.526 |
| Price To Operating Cash Flow Ratio | -0.152 | ▲48.491 | ▲138.627 |
| Debt To Assets Ratio | 0.278 | ▼-0.175 | ▲0.060 |
| Debt To Equity Ratio | 2.463 | ▲4.485 | ▲2.247 |
| Debt To Capital Ratio | 0.711 | ▼-1.267 | ▲0.080 |
| Long Term Debt To Capital Ratio | 0.000 | ▼-12.141 | ▼-2.521 |
| Financial Leverage Ratio | 8.869 | ▲13.335 | ▲7.105 |
| Working Capital Turnover Ratio | -0.003 | ▲0.193 | ▼-0.041 |
| Operating Cash Flow Ratio | -0.636 | ▼-0.156 | ▲1.750 |
| Operating Cash Flow Sales Ratio | -246.932 | ▼-241.389 | ▼-194.543 |
| Free Cash Flow Operating Cash Flow Ratio | 1.000 | ▼-0.018 | ▼-0.258 |
| Debt Service Coverage Ratio | -0.703 | ▲3.001 | ▲39.032 |
| Interest Coverage Ratio | -9.004 | ▲16.444 | ▲39.868 |
| Short Term Operating Cash Flow Coverage Ratio | -1.967 | ▲0.286 | ▼-1.123 |
| Operating Cash Flow Coverage Ratio | -1.967 | ▼-0.928 | ▼-0.327 |
| Capital Expenditure Coverage Ratio | -4463872.333 | ▼-4463817.951 | ▼-3571039.617 |
| Dividend Paid And Capex Coverage Ratio | -4463872.333 | ▼-4463817.951 | ▼-3571039.617 |
| Dividend Payout Ratio | 0.000 | 0.000 | 0.000 |
| Enterprise Value Multiple | -1.216 | ▲24.111 | ▲111.622 |
Key metrics
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Market cap | $2.0M | $692.1M | $1.77B | $2.74B | $3.32B | |
| Enterprise value | $6.9M | $701.1M | $1.77B | $2.73B | $3.31B | |
| EV / Sales | 127.08x | 273.14x | 623.00x | 405.78x | 0.00x | |
| EV / Op. cash flow | -0.52x | -49.28x | -78.64x | -262.63x | -301.35x | |
| EV / Free cash flow | -0.52x | -48.39x | -61.65x | -132.02x | -300.06x | |
| EV / EBITDA | -1.22x | -25.33x | -75.09x | -194.06x | -268.50x | |
| Net debt / EBITDA | -0.86x | -0.33x | -0.12x | 1.13x | 0.95x | |
| Current ratio | 0.11x | 0.19x | 0.73x | 11.52x | 17.44x | |
| Income quality | 1.68x | 0.47x | 0.90x | 0.70x | 0.85x | |
| Graham net-net | -$57 | -$5 | -$2 | $4 | $6 | |
| Tax burden | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | |
| Interest burden | 118.6% | 104.0% | 101.1% | 100.9% | 100.0% | |
| Working capital | -$18.8M | -$23.9M | -$2.3M | $31.1M | $38.2M | |
| Invested capital | $2.1M | -$1.0M | $18.1M | $41.9M | $39.3M | |
| Return on assets | -32.5% | -99.3% | -87.7% | -31.8% | -24.0% | |
| Operating ROA | -41.1% | -100.4% | -68.3% | -30.1% | -38.8% | |
| Return on tangible assets | -32.5% | -99.3% | -87.7% | -31.8% | -24.0% | |
| Return on equity | -287.9% | 443.5% | -185.7% | -39.8% | -25.1% | |
| Return on invested capital | -109.7% | -425.9% | -130.1% | -34.4% | -26.1% | |
| Return on capital employed | -325.6% | -4851.1% | -130.1% | -34.4% | -26.1% | |
| Earnings yield | -391.2% | -4.3% | -1.4% | -0.5% | -0.4% | |
| Free cash flow yield | -658.1% | -2.1% | -1.6% | -0.8% | -0.3% | |
| Capex / Op. cash flow | -0.0% | -1.8% | -27.5% | -98.9% | -0.4% | |
| Capex / Depreciation | 0.0% | 22.1% | 546.4% | 1431.4% | 8.7% | |
| Capex / Sales | 0.0% | 10.2% | 218.3% | 152.9% | 0.0% | |
| SG&A / Sales | 14200.6% | 855.0% | 460.4% | 118.8% | 0.0% | |
| R&D / Sales | 10036.3% | 248.9% | 270.1% | 138.9% | 0.0% | |
| Stock comp / Sales | 1417.3% | 39.3% | 35.3% | 16.7% | 0.0% | |
| Intangibles / Total assets | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | |
| Days sales outstanding | 217d | 83d | 197d | 23d | 0d | |
| Days payables outstanding | 110573d | 5071d | 987d | 108d | 0d | |
| Operating cycle | 217d | 83d | 197d | 146d | 0d | |
| Cash conversion cycle | -110357d | -4988d | -789d | 38d | 0d |
Change by theme
Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.
Change over 1 year
Change over 5 years
Employee count
Peer market caps
Recent news
- 2026-10-12 HCW Biologics Inc. (NASDAQ:HCWB) Shares Shorted: Short Interest Up 557.1% in September HCW Biologics Inc. (NASDAQ: HCWB - Get Free Report) was the target of a large increase in short interest during the month of September. As of September 30th, there was short interest totaling 60,941 shares, an increase of 557.1% from the September 15th total of 9,274 shares. Based on an average daily trading volume, of 1,348,961
- 2026-10-09 HCW Biologics Maintains Momentum Toward Completion of IND Application for Clinical Study to Evaluate Lead T-Cell Engager in Solid Tumors Communication with FDA at recent Type B meeting provided clear guidance for next steps to prepare IND application to support first-in-human clinical study in cancer
- 2026-09-24 HCW Biologics Announces Pricing of $1.5 Million Private Placement MIRAMAR, Fla., Sept. 24, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”), (NASDAQ: HCWB), a clinical-stage biopharmaceutical company developing transformative fusion immunotherapeutics to treat autoimmune diseases, cancer and senescence-associated dysplasia, today announced the pricing of its $1.5 million private placement (the “Offering”) with an existing stockholder of the Company, (the “Investor”).
- 2026-09-08 HCW Biologics Entered an Exclusive Distribution Agreement with Akron Biotech to Commercialize HCW11-006 as Reagent Used to Support Production of Highly Functional Human CAR-T Cells Agreement includes pre-payment commitments for product sales and distribution of the second-generation multi-cytokine-based HCW11-006 for use as a reagent
- 2026-09-02 HCW Biologics Strengthens U.S. Patent Estate for Its Lead Clinical-Stage Immunotherapeutic HCW9302 as Alopecia Areata Treatment HCW9302 is a best-in-class IL-2-based immunotherapeutic for treatment of autoimmune diseases through expanding and activating regulatory T cells Patent allowance received for use of HCW9302 as treatment for alopecia areata Phase 1 dose-escalating clinical study evaluating HCW9302 as monotherapy in patients with alopecia areata on track for completion in Q4 2026, continues to be well tolerated with no dose-limiting toxicities Preliminary readout of first two dose cohorts is encouraging -- patients diagnosed with alopecia areata show positive response after single dose of monotherapy at 3 micrograms/kg dose level MIRAMAR, Fla., Sept. 02, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”) (NASDAQ: HCWB), a U.S.-based clinical-stage biopharmaceutical company focused on developing novel fusion immunotherapeutics to treat autoimmune diseases, cancer, and senescence-associated dysplasia, announced receipt of a Notice of Allowance from the U.S. Patent and Trademark Office (“USPTO”) for claims directed to use of HCW9302 to treat alopecia areata (U.S. Patent Application Publication No.
- 2026-08-25 HCW Biologics'' TGF-β Trap and IL-15 Fusion is a Novel Moiety to Enhance Immunotherapeutic Activity against Diseased Cells Human studies show that the TGF-β trap and IL-15 fusion used alone promotes expansion of progenitor CD8 + T cells and NK cells Company has incorporated the TGF-β/IL-15 moiety into the constructs of its second-generation fusion immunotherapeutics constructed with novel TRBC drug development platform MIRAMAR, Fla., Aug. 25, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”) (NASDAQ: HCWB), a U.S.-based clinical-stage biopharmaceutical company focused on developing novel fusion immunotherapeutics to treat autoimmune diseases, cancer, and senescence-associated dysplasia, together with collaborators at leading research institutions, have identified a TGF-β trap and IL-15 fusion as a novel moiety with potential applications against diseased cells and viral infections.
- 2026-08-14 HCW Biologics Reports Second Quarter 2026 Business and Clinical Development Highlights and Financial Results MIRAMAR, Fla., Aug. 14, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”) (NASDAQ: HCWB), a clinical-stage biopharmaceutical company focused on developing transformative fusion immunotherapeutics to treat autoimmune diseases, cancer and senescence-associated dysplasia, today reported financial results and recent business highlights for the three and six months ended June 30, 2026.
- 2026-07-29 HCW Biologics Inc. Announces Pricing of $1.6 Million Private Placement Offering MIRAMAR, Fla., July 29, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”), (NASDAQ: HCWB), a clinical-stage biopharmaceutical company developing transformative fusion immunotherapeutics to treat autoimmune diseases, cancer and senescence-associated dysplasia, today announced the pricing of its $1.6 million private placement offering (the “Offering”) with a group of investors, including officers, directors and an existing stockholder of the Company, (each, and “Investor” and collectively, the “Investors”). Pursuant to a securities purchase agreement entered into with the Investors (the “Purchase Agreement”), the Company agreed to issue and sell an aggregate of 618,682 units (the “Units”), with each Unit consisting of (i) one share of the Company''s common stock, par value $0.0001 per share (“Common Stock”), or, in lieu thereof, one pre-funded warrant to purchase one share of Common Stock (a “Pre-Funded Warrant”), and (ii) the right to receive one common stock purchase warrant (a “Common Warrant”) to purchase one share of Common Stock upon, and subject to, stockholder approval of the issuance thereof.
- 2026-07-23 HCW Biologics Reaches Milestones for Its Proprietary Tetravalent Second-Generation T-Cell Engager Program On Track To Initiate Clinical Trials in First Half 2027 Company requested Type B pre-IND meeting with U.S. FDA to discuss development and regulatory strategy for its investigational tetravalent T-cell engager, HCW11-018b HCW11-018b has demonstrated potential for treating solid tumors that overexpress human tissue factor, including gynecologic and pancreatic cancers Company has developed a streamlined, robust manufacturing process designed to produce high-quality cGMP material at a lower cost than current methods MIRAMAR, Fla., July 23, 2026 (GLOBE NEWSWIRE) -- HCW Biologics Inc. (the “Company” or “HCW Biologics”), (NASDAQ: HCWB), a U.S.-based clinical-stage biopharmaceutical company developing transformative fusion immunotherapeutics to treat diseases promoted by chronic inflammation, focusing on autoimmune disorders and other inflammatory diseases, cancer and senescence-associated dysplasia, today announced that it has requested a Type B (pre-IND application) meeting with the U.S. FDA to discuss the development and regulatory strategy for its investigational lead product candidate, HCW11-018b, a tetravalent T-cell engager (“TCE”) constructed with the Company''s proprietary TRBC drug development platform.