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CSTL

Bearish signalScored 2026-10-25 Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

Research, not advice.

À propos

Castle Biosciences, Inc.

Nom
Castle Biosciences, Inc.
Secteur
Healthcare
Industrie
Medical - Diagnostics & Research
Bourse
NASDAQ
Capitalisation
$1.0B
Employés
1,002
PDG
Derek J. Maetzold
Site web
https://castlebiosciences.com
Marché
BDSXBIAFFRNMGHMDXHMYGN

Castle Biosciences, Inc. functions as a commercial-stage diagnostics firm, with its primary objective being the provision of both diagnostic and prognostic testing services, specifically targeting various dermatological cancers. Their flagship product, DecisionDx-Melanoma, represents an advanced multi-gene expression profile (GEP) assay engineered to assess the probability of metastasis in patients afflicted with invasive cutaneous melanoma. In addition to their leading solution, the company has created several other specialized, proprietary tests. Among these is DecisionDx-UM, a GEP test tailored to forecast the risk of metastasis for individuals with uveal melanoma, a less common malignancy of the eye. Another key offering is DecisionDx-SCC, a distinctive 40-gene expression profile test that utilizes a patient's unique tumor biology to predict their specific risk of squamous cell carcinoma metastasis, particularly for those presenting with recognized risk factors. Moreover, they offer DecisionDx DiffDx-Melanoma and myPath Melanoma, both proprietary GEP tests employed to assist in the accurate diagnosis of ambiguous pigmented lesions. These specialized testing services are provided by Castle Biosciences to patients predominantly through their healthcare providers. The organization commenced operations in 2007 and maintains its corporate headquarters in Friendswood, Texas.

Price (1 year)

Live chart from TradingView — independent market data, as price context around the filings, not the Quorum score. EMA 50/200 and Bollinger load by default. When the exchange is known it is sent as EXCHANGE:SYMBOL; otherwise TradingView resolves the ticker best-effort.

VENTE TOTALE: 34 324 titres (~1 156 797,80 $ US)

Insiders
MAETZOLD DEREK J
Total bought
—

Avg buy (VWAP, 90d window) —

Total sold
$4,446,004

Avg sell (VWAP, 90d window) $32.40 vs last close $33.30 (+2.8%)

Total sold sums Form 4 code S in this window. Codes F, M, A and G are left out.

$2,838,198 of that total is under a Rule 10b5-1 plan. It is shown here and left out of the score.

Last activity
2026-10-19
Liquidity
Thin $11,367,834/day · 20d vol
Last synced
2026-10-26 21:10:20 Synced via automated research pipeline

Sign in to request a sync of this company's price history and timing levels.

Insider holdings as a share of total assets aren't available for this company.

Avg buy and avg sell are volume-weighted prices (sum of shares × price, divided by shares) for Form 4 rows in this 90-day window that report both figures. A comparison with last close is market context for that average, not advice.

Recent Form 4

Filings in the 90-day window for this company. Value is shares × price from the filing. Research, not advice.

Date Person Side Shares Price Value Form 4
2026-10-19 MAETZOLD DEREK J Sell · S 8,580 $31.91 $273,788 Form 4
2026-10-12 Juvenal Tobin W Sell · S · 10b5-1 3,288 $33.64 $110,608 Form 4
2026-10-05 MAETZOLD DEREK J Sell · S · 10b5-1 8,580 $35.57 $305,156 Form 4
2026-10-01 Oelschlager Kristen M Sell · S · 10b5-1 1,346 $36.38 $48,967 Form 4
2026-09-30 Juvenal Tobin W Sell · S · 10b5-1 1,034 $34.20 $35,363 Form 4
2026-09-29 Juvenal Tobin W Sell · S · 10b5-1 5,543 $35.50 $196,765 Form 4
2026-09-21 MAETZOLD DEREK J Sell · S · 10b5-1 8,580 $35.33 $303,166 Form 4
2026-09-15 Juvenal Tobin W Sell · S · 10b5-1 3,294 $35.14 $115,758 Form 4
2026-09-14 Juvenal Tobin W Sell · S · 10b5-1 3,306 $32.32 $106,863 Form 4
2026-09-11 MAETZOLD DEREK J Sell · S · 10b5-1 223 $32.78 $7,310 Form 4
2026-09-01 Oelschlager Kristen M Sell · S · 10b5-1 200 $34.02 $6,804 Form 4
2026-08-31 Juvenal Tobin W Sell · S · 10b5-1 1,730 $32.81 $56,761 Form 4
2026-08-28 MAETZOLD DEREK J Sell · S · 10b5-1 956 $33.88 $32,389 Form 4
2026-08-25 Juvenal Tobin W Sell · S · 10b5-1 9,050 $35.04 $317,112 Form 4
2026-08-25 Oelschlager Kristen M Sell · S 5,223 $34.64 $180,919 Form 4
2026-08-24 Oelschlager Kristen M Sell · S 12,218 $33.69 $411,588 Form 4
2026-08-17 Juvenal Tobin W Sell · S · 10b5-1 1,730 $29.59 $51,191 Form 4
2026-08-14 MAETZOLD DEREK J Sell · S · 10b5-1 1,100 $30.02 $33,022 Form 4
2026-08-14 Stokes Frank Sell · S 24,908 $29.77 $741,511 Form 4
2026-08-05 MAETZOLD DEREK J Sell · S · 10b5-1 2,546 $30.68 $78,114 Form 4
2026-08-04 MAETZOLD DEREK J Sell · S · 10b5-1 11,935 $31.34 $373,995 Form 4
2026-08-03 Oelschlager Kristen M Sell · S · 10b5-1 1,100 $30.62 $33,682 Form 4
2026-08-03 Juvenal Tobin W Sell · S · 10b5-1 1,730 $28.25 $48,872 Form 4
2026-08-03 MAETZOLD DEREK J Sell · S · 10b5-1 10,664 $30.35 $323,684 Form 4
2026-07-31 Juvenal Tobin W Sell · S · 10b5-1 1,891 $30.26 $57,229 Form 4
2026-07-31 MAETZOLD DEREK J Sell · S · 10b5-1 6,480 $30.15 $195,385 Form 4
2026-07-27 MAETZOLD DEREK J Sell · S · 10b5-1 232 $25.06 $5,814 Form 4
2025-11-24 Juvenal Tobin W Sell · S · 10b5-1 1,301 $38.39 $49,945 Form 4

Sales marked 10b5-1 are scheduled in advance and don't count toward the Quorum score. Les ventes marquées 10b5-1 sont planifiées à l'avance et ne pèsent pas dans le score Quorum.

Congressional trades

STOCK Act disclosures (90-day window)

Amounts are STOCK Act brackets as disclosed. Quorum does not turn a bracket into an exact price or a midpoint.

No STOCK Act disclosures for this company in this window.

Recent trades

DateRepresentativeTypeAmount
2022-03-15Josh GottheimerSale (Partial)$1,001 - $15,000
2020-12-23Gilbert CisnerosPurchase$1,001 - $15,000
2020-12-21Josh GottheimerPurchase$1,001 - $15,000

Signal

Bearish signalScored 2026-10-25 Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

CSTL combines a weak catalyst score (25) driven by heavy insider selling and no actionable event trigger with deteriorating fundamentals — a return to net losses in 2025 and negative EPS undermine the strong balance…

The first sentence of the analysis written for CSTL on 2026-10-25 - a real excerpt, not a sample. The rest of it, the 0-100 score and the rating it produced are part of Plus. See plans.

Bearish signal Drivers: trend, fundamentals. Moteurs : tendance, fondamentaux.

Factor checklist — research, not advice

A check leans with a bullish reading. A cross leans against it. A dash is unavailable or mixed.

  • Insider Pulls against a bullish reading. Selling cluster — sale value, no purchase value
  • Narrative Pulls against a bullish reading. Stored narrative reading is in the bearish band
  • Congress Unavailable or mixed. No purchase disclosures in the stored window
  • Timing Pulls against a bullish reading. Close is more than 0.5 ATR under stored support
  • Financial indicators Unavailable or mixed. Current ratio 5.26 · operating margin -12% — readings disagree

Suggested stop 30.74, nearest stored support minus 0.5 ATR(7.7% under the last close). Reward/risk to the next stored resistance is 1.83. Wait — that reward/risk is under 2. Research, not advice. Not an order.

Recent news

Market snapshot

Financial ratios

MetricTrend2025-12-312024-12-312023-12-312022-12-312021-12-31
Gross Profit Margin79.4%81.9%79.5%76.6%83.2%
Ebit Margin-8.5%6.7%-26.1%-50.3%-42.5%
Ebitda Margin3.3%11.5%-20.5%-42.6%-38.9%
Operating Profit Margin-12.4%2.6%-30.9%-53.2%-42.6%
Pretax Profit Margin-8.6%6.5%-26.1%-50.3%-42.5%
Continuous Operations Profit Margin-7.0%5.5%-26.1%-49.0%-33.3%
Net Profit Margin-7.0%5.5%-26.1%-49.0%-33.3%
Bottom Line Profit Margin-7.0%5.5%-26.1%-49.0%-33.3%
Current Ratio5.2587.2926.2028.09014.215
Quick Ratio5.1097.1276.0357.98014.133
Solvency Ratio0.1540.454-0.727-1.175-0.549
Cash Ratio1.7002.4242.0743.40313.246
Price To Earnings Ratio-46.86740.379-10.084-9.124-34.573
Price To Earnings Growth Ratio0.208-0.3090.591-0.084-0.267
Forward Price To Earnings Growth Ratio0.208-0.3090.591-0.084-0.267
Price To Earnings Diluted Ratio-46.86742.984-10.084-9.124-34.573
Price To Earnings Diluted Growth Ratio0.200-0.3330.591-0.084-0.267
Price To Book Ratio2.3951.6241.4781.5372.617
Price To Sales Ratio3.2762.2292.6324.47511.454
Price To Free Cash Flow Ratio39.80620.258-30.051-12.970-47.967
Price To Operating Cash Flow Ratio17.52311.412-102.806-14.724-56.768
Debt To Assets Ratio0.0640.0500.0340.0300.018
Debt To Equity Ratio0.0780.0580.0390.0340.020
Debt To Capital Ratio0.0730.0550.0380.0320.020
Long Term Debt To Capital Ratio0.0200.0210.0000.0000.000
Financial Leverage Ratio1.2291.1651.1591.1211.123
Working Capital Turnover Ratio1.1411.1890.8720.4680.255
Operating Cash Flow Ratio0.9371.313-0.118-1.153-0.763
Operating Cash Flow Sales Ratio0.1870.195-0.026-0.304-0.202
Free Cash Flow Operating Cash Flow Ratio0.4400.5633.4211.1351.183
Debt Service Coverage Ratio33.19940.724-4,102.273-3,328.118-27,884.000
Interest Coverage Ratio-497.79115.026-6,179.727-4,285.588-40,079.000
Short Term Operating Cash Flow Coverage Ratio154.309233.3310.0000.0000.000
Operating Cash Flow Coverage Ratio1.7432.462-0.367-3.109-2.314
Capital Expenditure Coverage Ratio1.7862.290-0.413-7.396-5.450
Dividend Paid And Capex Coverage Ratio1.7862.290-0.413-7.396-5.450
Dividend Payout Ratio0.0000.0000.0000.0000.000
Enterprise Value Multiple92.36916.961-10.991-8.634-20.659

Sparkline shows each ratio oldest → newest (left → right).

How the latest year compares

For each ratio: its most recent value, the change versus one year earlier, and versus its 5-year average. ▲ higher ▼ lower

MetricCurrentvs 1Y agovs 5Y avg
Gross Profit Margin 79.4% ▼-2.5% ▼-0.8%
Ebit Margin -8.6% ▼-15.2% ▲15.6%
Ebitda Margin 3.3% ▼-8.2% ▲20.7%
Operating Profit Margin -12.4% ▼-15.0% ▲14.9%
Pretax Profit Margin -8.6% ▼-15.1% ▲15.6%
Continuous Operations Profit Margin -7.0% ▼-12.5% ▲15.0%
Net Profit Margin -7.0% ▼-12.5% ▲15.0%
Bottom Line Profit Margin -7.0% ▼-12.5% ▲15.0%
Current Ratio 5.258 ▼-2.034 ▼-2.953
Quick Ratio 5.109 ▼-2.018 ▼-2.968
Solvency Ratio 0.154 ▼-0.300 ▲0.523
Cash Ratio 1.700 ▼-0.724 ▼-2.869
Price To Earnings Ratio -46.867 ▼-87.246 ▼-34.814
Price To Earnings Growth Ratio 0.208 ▲0.516 ▲0.180
Forward Price To Earnings Growth Ratio 0.208 ▲0.516 ▲0.180
Price To Earnings Diluted Ratio -46.867 ▼-89.851 ▼-35.335
Price To Earnings Diluted Growth Ratio 0.200 ▲0.534 ▲0.179
Price To Book Ratio 2.395 ▲0.771 ▲0.465
Price To Sales Ratio 3.276 ▲1.046 ▼-1.538
Price To Free Cash Flow Ratio 39.806 ▲19.548 ▲45.991
Price To Operating Cash Flow Ratio 17.523 ▲6.111 ▲46.596
Debt To Assets Ratio 0.064 ▲0.014 ▲0.025
Debt To Equity Ratio 0.078 ▲0.021 ▲0.033
Debt To Capital Ratio 0.073 ▲0.018 ▲0.029
Long Term Debt To Capital Ratio 0.020 ▼-0.001 ▲0.012
Financial Leverage Ratio 1.229 ▲0.063 ▲0.069
Working Capital Turnover Ratio 1.141 ▼-0.047 ▲0.356
Operating Cash Flow Ratio 0.937 ▼-0.376 ▲0.894
Operating Cash Flow Sales Ratio 0.187 ▼-0.008 ▲0.217
Free Cash Flow Operating Cash Flow Ratio 0.440 ▼-0.123 ▼-0.908
Debt Service Coverage Ratio 33.199 ▼-7.525 ▲7081.292
Interest Coverage Ratio -497.791 ▼-512.817 ▲9707.625
Short Term Operating Cash Flow Coverage Ratio 154.309 ▼-79.022 ▲76.781
Operating Cash Flow Coverage Ratio 1.743 ▼-0.719 ▲2.060
Capital Expenditure Coverage Ratio 1.786 ▼-0.504 ▲3.623
Dividend Paid And Capex Coverage Ratio 1.786 ▼-0.504 ▲3.623
Dividend Payout Ratio 0.000 0.000 0.000
Enterprise Value Multiple 92.369 ▲75.408 ▲78.560

Key metrics

MetricTrend20252024202320222021
Market cap$1.13B$740.2M$578.4M$613.3M$1.08B
Enterprise value$1.05B$646.9M$494.9M$503.8M$756.2M
EV / Sales3.04x1.95x2.25x3.68x8.04x
EV / Op. cash flow16.28x9.97x-87.96x-12.09x-39.84x
EV / Free cash flow36.99x17.70x-25.71x-10.65x-33.66x
EV / EBITDA92.37x16.96x-10.99x-8.63x-20.66x
Net debt / EBITDA-7.04x-2.45x1.85x1.88x8.78x
Current ratio5.26x7.29x6.20x8.09x14.21x
Income quality-2.66x3.56x0.10x0.62x0.61x
Graham number—$16———
Graham net-net$8$9$8$9$12
Tax burden81.9%84.6%100.2%97.4%78.2%
Interest burden100.3%97.4%100.0%100.0%100.0%
Working capital$292.4M$310.8M$248.0M$256.2M$328.9M
Invested capital$504.2M$479.7M$403.0M$409.0M$434.7M
Return on assets-4.2%3.4%-12.7%-15.0%-6.8%
Operating ROA-7.7%1.8%-15.1%-16.0%-8.9%
Return on tangible assets-5.0%4.3%-17.1%-20.9%-8.4%
Return on equity-5.1%4.0%-14.7%-16.8%-7.6%
Return on invested capital-6.8%1.5%-16.7%-17.2%-7.1%
Return on capital employed-8.4%1.8%-16.8%-17.7%-9.2%
Earnings yield-2.1%2.5%-9.9%-10.9%-2.9%
Free cash flow yield2.5%4.9%-3.3%-7.7%-2.1%
Capex / Op. cash flow56.0%43.7%-242.1%-13.5%-18.3%
Capex / Depreciation88.3%177.1%110.5%53.4%102.2%
Capex / Sales10.5%8.5%6.2%4.1%3.7%
SG&A / Sales66.6%60.2%82.0%104.4%92.2%
R&D / Sales15.1%15.7%24.4%32.8%31.5%
Stock comp / Sales13.3%15.2%23.3%26.5%23.1%
Intangibles / Total assets17.2%20.0%25.9%28.2%19.2%
Days sales outstanding46d56d64d63d67d
Days payables outstanding96d42d83d54d59d
Operating cycle99d106d128d108d114d
Cash conversion cycle3d64d45d54d55d

Change by theme

Grouped by what each metric measures. Each figure is the change over the period shown — ▲ up ▼ down versus then.

Change over 1 year

Valuation
Market cap ▲+52.3%EV / Sales ▲+56.3%EV / EBITDA ▲+444.6%EV / Op. cash flow ▲+6.310Earnings yield ▼-0.046
Profitability
Return on equity ▼-0.091Return on assets ▼-0.076Return on invested capital ▼-0.084Return on capital employed ▼-0.102Operating ROA ▼-0.095Income quality ▼-6.219Tax burden ▼-0.028
Efficiency
Days sales outstanding ▼-10.298Days payables outstanding ▲+54.314Operating cycle ▼-6.924Cash conversion cycle ▼-61.238Capex / Sales ▲+0.019R&D / Sales ▼-0.006
Balance-sheet strength
Current ratio ▼-2.034Net debt / EBITDA ▼-4.589Working capital ▼-18342000.000Invested capital ▲+24535000.000Intangibles / Total assets ▼-0.028

Change over 5 years

Valuation
Market cap ▲+4.6%EV / Sales ▼-62.1%EV / EBITDA ▲+547.1%EV / Op. cash flow ▲+56.118Earnings yield ▲+0.008
Profitability
Return on equity ▲+0.025Return on assets ▲+0.026Return on invested capital ▲+0.003Return on capital employed ▲+0.008Operating ROA ▲+0.012Income quality ▼-3.270Tax burden ▲+0.036
Efficiency
Days sales outstanding ▼-21.045Days payables outstanding ▲+37.418Operating cycle ▼-14.975Cash conversion cycle ▼-52.393Capex / Sales ▲+0.068R&D / Sales ▼-0.164
Balance-sheet strength
Current ratio ▼-8.957Net debt / EBITDA ▼-15.818Working capital ▼-36437000.000Invested capital ▲+69569000.000Intangibles / Total assets ▼-0.020

Employee count

Peer market caps